Browsing by Author "10056173 - Malan, Nicolaas Theodor"
Now showing items 21-40 of 93
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Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: the SABPA Study
Malan, N.T.; Hamer, M.; Schutte, A.E.; Huisman, H.W.; Schutte, R.; Smith, W.; Mels, C.M.C.; Van Rooyen, J.M.; Malan, L. (Nature Publishing Group, 2014)It is known that low testosterone (T) and high cortisol levels are associated with hypertension as well as with chronic stress, linking stress with elevated blood pressure (BP). However, the association between acute ... -
Classifying Africans with the Metabolic Syndrome
Schutte, A.E.; Schutte, R.; Huisman, H.W.; Van Rooyen, J.M.; Malan, L.; Olckers, A.; Malan, N.T. (Thieme, 2009)This study was aimed to compare prevalences of the metabolic syndrome in Africans using five definitions as proposed by the World Health Organization (WHO), the European Group for the Study of Insulin Resistance (EGIR), ... -
Cohort profile: sympathetic activity and ambulatory blood pressure in Africans (SABPA) prospective cohort study
Malan, Leoné; Hamer, Mark; Steyn, Hendrik S.; Malan, Nicolaas T.; Frasure-Smith, Nancy (Oxford Univ Press, 2015)Adapting to an over–demanding stressful urban environment may exhaust the psychophysiological resources to cope with these demands, and lead to sympathetic nervous system dysfunction. The evidence that an urban–dwelling ... -
Comparison of central pressure estimates obtained from SphygmoCor, Omron HEM-9000AI and carotid applanation tonometry
Kips, Jan G.; Schutte, Aletta E.; Huisman, Hugo W.; Van Rooyen, Johannes M.; Fourie, Catharina M.; Malan, Leoné; Schutte, Rudolph (Lipppincott, Williams & Wilkins, 2011)Background: The Omron HEM-9000AI is the first automated tonometer to provide an estimate of central SBP (cSBP), which is considered to be more predictive of cardiovascular events than brachial pressure. However, considerable ... -
Comparison of Telomere Length in Black and White Teachers From South Africa: the Sympathetic Activity and Ambulatory Blood Pressure in Africans Study
Von Kanel, Roland; Malan, Nicolaas Theodor; Hamer, Mark; Malan, Leoné (Lippincott Williams & Wilkins, 2015)Objective: Telomere length is a marker of biological aging that has been linked to cardiovascular disease risk. The black South African population is witnessing a tremendous increase in the prevalence of cardiovascular ... -
Compromised bioavailable IGF-1 of black men relates favourably to ambulatory blood pressure: the SABPA study
Schutte, A.E.; Schutte, R.; Smith, W.; Huisman, H.W.; Mels, C.M.C.; Malan, L.; Fourie, C.M.T.; Malan, N.T.; Van Rooyen, J.M.; Kruger, R. (Elsevier, 2014)Objectives Insulin-like growth factor-1 (IGF-1) has potent endothelial-protective, anti-platelet and anti-thrombotic activities, and also exerts mitogenic and proliferatory actions on vascular smooth muscle cells. Conflicting ... -
Conventional and behavioral risk factors explain differences in sub-clinical vascular disease between black and Caucasian South Africans: the SABPA study
Hamer, M.; Malan, L.; Schutte, A.E.; Huisman, H.W.; Van Rooyen, J.M.; Schutte, Rudolph; Fourie, C.M.T.; Malan, N.T.; Seedat, Y.K. (Elsevier, 2011)Conventional and behavioral risk factors explain differences in sub-clinical vascular disease between black and Caucasian South Africans: The SABPA study Objectives: There is an emerging burden of cardiovascular disease ... -
Coping and autonomic dysfunction act in tandem with alcohol-related subclinical atherosclerosis: the SAPBA study
Malan, L.; Oosthuizen, W.; Scheepers, J.D.; Malan, N.T. (Nova Science Publishers, 2014)"Introduction: Alcohol abuse is among the Westernized world‘s most common lifestyle factors contributing to sensitization of vascular structure and pathology. Gamma glutamyl transferase (γ-GT), as a marker of alcohol abuse, ... -
Coping and metabolic syndrome indicators in urban black South African men: the SABPA study
Du Plessis, A.; Malan, L.; Malan, N.T. (Clinics Cardiv Publishing, 2010)Urbanisation is associated with obesity, hypertension anddevelopment of the metabolic syndrome (MS). We aimed toassess the use of different coping styles and their influenceon increases in MS indicators and target end-organ ... -
Coping facilitated troponin T increases and hypo-responsivity in the copeptin-HPA-axis during acute mental stress in a black cohort: the SABPA study
Myburgh, Catharina Elizabeth; Malan, Leoné; Möller, Marisa; Steyn, Faans; Malan, Nicolaas Theodor (Elsevier, 2019)Background Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an ... -
Coping mechanisms, perception of health and cardiovascular dysfunction in Africans
Malan, Leoné; Schutte, Aletta Elisabeth; Malan, Nicolaas Theodor; Wissing, Maria Philipina; Vorster, Hester Hendrina; Steyn, Hendrik Stefanus; Van Rooyen, Johannes Marthinus; Huisman, Hugo Willem (Elsevier, 2006)The purpose of this study was to compare active and passive coping strategies of Africans with perception of own health and cardiovascular data. The subjects included 236 apparently healthy Africans (men = 109; women = 127). ... -
Coping with urbanization: a cardiometabolic risk? The THUSA study
Malan, Leoné; Malan, Nicolaas T.; Wissing, Maria P.; Seedat, Yackoob K. (Elsevier, 2008)An assessment of specific coping styles in rural-urban Africans is done to evaluate its contribution as cardiometabolic risk factor. In total, 608 apparently healthy Africans were included in a cross-sectional comparative ... -
Coping, copeptin and cardiac stress: the SABPA study
Myburgh, Catharina Elizabeth (North-West University (South-Africa). Potchefstroom Campus, 2019-05)Coping met emosionele stres kan óf effektief wees vir die neutralisering van stres óf dit kan negatiewe kardiovaskulêre uitkomste fasiliteer. Verdedigende-coping (DefS) en sosiale ondersteunings-coping is op effektiewe ... -
Cornell product relates to albuminuria in hypertensive black adults independently of blood pressure: the SABPA study
Schutte, Rudolph; Huisman, Hugo W.; Ware, Lisa J.; Mels, Catherina M.C.; Smith, Wayne; Malan, Nicolaas T.; Malan, Leoné; Van Rooyen, Johannes M.; Fourie, Carla M.T.; Kruger, Ruan; Botha, Shani; Schutte, Aletta E. (Elsevier, 2015)Evidence of the relationship between left ventricular hypertrophy and urinary albumin excretion is contradictory and limited in black adults in whom hypertensive heart disease is common. We aimed to investigate the ... -
Correction to: Heart rate variability, the dynamic nature of the retinal microvasculature and cardiac stress: providing insight into the brain–retina–heart link: the SABPA study
Wentzel, Annemarie; Malan, Leoné; Von Känel, Roland; Smith, Wayne; Malan, Nicolaas T. (Springer, 2020)Correction to: Eye https://doi.org/10.1038/s41433-019-0515-y Since the online publication of this article, the authors have noticed that the conclusion to the abstract contains an error. The correct abstract conclusion ... -
Cortisol: brain-derived neurotrophic factor ratio associated with silent ischaemia in a black male cohort: the SABPA study
Schutte, Christiaan E.; Malan, Leoné; Scheepers, Jacobus D.; Oosthuizen, Woudri; Cockeran, Maricke; Malan, Nicolaas T. (SASA, 2016)Aim: Emotional distress has been associated with cardiovascular disease (CVD) in Africans. Cortisol and brain-derived neurotrophic factor (BDNF), as markers of emotional distress, increase cardiometabolic risk. We therefore ... -
The cost of coping: a cardio-neuro-metabolic risk for black South Africans?
Malan, Leoné; Malan, N.T.; Du Plessis, A.; Wissing, M.P.; Potgieter, J.C.; Seedat, Y.K. (Clinics Cardiv Publishing, 2010)Psychosocial stress is a contributing factor to cardiovascular disease. An important way of investigating the mechanisms underlying this association is acute psycho-physiological stress testing, involving measurement of ... -
Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: the SABPA study
Malan, L.; Hamer, M.; Steyn, H.S.; Schutte, R.; Smith, W.; Van Rooyen, J.M.; Fourie, C.M.T.; Malan, N.T. (Elsevier, 2013)Background: Dissociation between behavioural defensive active coping (AC) control albeit physiological “loss of control” responses was associated with silent ischaemia and structural wall abnormalities in African men. Whether ... -
Defensive coping and essential amino acid markers as possible predictors for structural vascular disease in an African and Caucasian male cohort: the SABPA study
Möller, Marisa; Malan, Leoné; Mels, Carina M.C.; Malan, Nico T.; Magnusson, Martin (Wiley, 2017)Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative ... -
Defensive coping and renovascular disease risk. Adrenal fatigue in a cohort of Africans and Caucasians: the SABPA study
De Kock, Andrea; Malan, Leoné; Hamer, Mark; Cockeran, Marike; Malan, Nico T. (Elsevier, 2015)Background: Defensive coping is an established cardiovascular risk factor in Africans. Additionally, chronic, excessive or inadequate hypothalamic pituitary adrenal axis (HPAA) stress responses could either increase or ...