Browsing by Subject "Antidepressants"
Now showing items 1-10 of 13
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An analysis of antidepressant noncompliance in the private health sector of South Africa
(2014)The main aim of the thesis was to measure antidepressant (AD) non-compliance, to determine which factors are closely associated with AD non-compliance and the consequences of prolonged AD non-compliance in the private ... -
Antidepressant usage by South African children and adolescents : a drug utilisation review
(2013)This study set out to review and analyse aspects of antidepressant prescribing in children and adolescents in a section of the private health care sector of South Africa. The research was conducted in two phases, namely a ... -
A cost minimisation analysis of the usage of central nervous system medicines by using a managed care medicine price list
(North-West University, 2004)Increasing health care costs is an international problem from which South Africa is not excluded. Prescription medication contributes most to these high health care costs, and methods to reduce their costs to society are ... -
Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression
(Springer, 2016)Rationale The mechanisms mediating ketamine’s antidepressant effect have only been partly resolved. Recent preclinical reports implicate serotonin (5-hydroxytryptamine; 5-HT) in the antidepressant-like action of ketamine. ... -
The effect of Boophone disticha on the regulation of Brain Derived Neurotrophic Factor gene expression in BALB/c mouse model of depression
(North-West University (South Africa), 2022)The mental disorder of depression ranks high amongst heterogeneous and disabling conditions on earth. As a complex disease, depression can be characterized by combinations of genetic and environmental factors. The current ... -
Effects of an antidepressant mixture on the brain serotonin and predation behavior of hybrid striped bass
(Wiley, 2016)Antidepressants have been found in measurable concentrations in final treated wastewater effluent and receiving waters throughout the world. Studies have shown that these concentrations are typically not overtly toxic, but ... -
Evaluation of indigenous medicinal plants with potential antidepressant effects
(North-West University (South Africa), 2023)Major depressive disorder (MDD) is a common mental health condition that represents one of the foremost causes of disease burden worldwide, including in South Africa. The search for safe and potent natural-based treatment ... -
The impact of HIV/AIDS on compliance with antidepressant treatment in major depressive disorder: a prospective study in a South African private healthcare cohort
(BioMed Central, 2015)Background: MDD and HIV/AIDS have a high prevalence worldwide with severe consequences for patients. In both conditions, compliance with treatment is key to successfully treat these disorders. In the current study, ... -
Major depression and models for new generations effective antidepressants / Christiaan Beyers Brink
(Potchefstroom : Noordwes-Universiteit, Potchefstroomkampus (Suid-Afrika), 2009)(Afrikaans follows English / Afrikaans volg Engels) Major depression is a severe mood disorder, affecting the lives of more than a hundred million people world-wide, including in Africa. Yet existing effective treatment ... -
Overview of antidepressant usage and cost 2004 until 2006
(North-West University, 2007)Depression has an increasingly significant economic impact and quality of life burden on patients, employers and third party payers worldwide (Hylan et a/., 1998:53). Current projections indicate that the global burden of ...