Browsing by Subject "Azure B"
Now showing items 1-7 of 7
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The antidepressant properties of selected methylene blue analogues
(2014)The shortcomings of current antidepressant agents prompts the design of novel multimodal antidepressants and the identification of new antidepressant targets, especially those located at sub-cellular level. Such ... -
Azure B and a synthetic structural analogue of methylene blue, ethylthioninium chloride, present with antidepressant-like properties
(Elsevier, 2014)Aims: The phenothiazinium compound, methylene blue (MB), possesses diverse pharmacological actions and is attracting attention for the treatment of bipolar disorder and Alzheimer's disease. MB acts on both monoamine oxidase ... -
Azure B, a metabolite of methylene blue, is a high-potency, reversible inhibitor of monoamine oxidase
(Elsevier, 2012)Methylene blue (MB) has been shown to act at multiple cellular and molecular targets and as a result possesses diverse medical applications. Among these is a high potency reversible inhibition of monoamine oxidase A ... -
The development of simple HPLC methods to separate methylene blue and its metabolites
(North-West University (South Africa), Potchefstroom Campus, 2018)The possible treatment and prevention of Alzheimer’s disease (AD) is one of many clinical applications of methylene blue (MB) that has recently attracted much interest. Due to its ability to interact with various targets, ... -
The development of simple HPLC methods to separate methylene blue and its metabolites
(North-West University, 2018)The possible treatment and prevention of Alzheimer’s disease (AD) is one of many clinical applications of methylene blue (MB) that has recently attracted much interest. Due to its ability to interact with various targets, ... -
The interactions of azure B, a metabolite of methylene blue, with 2 acetylcholinesterase and butyrylcholinesterase
(Elsevier, 2014)Methylene blue(MB) is reported to possess diverse pharmacological actions and is attracting increasing attention for the treatment of neurodegenerative disorders such as Alzheimer's disease. Among the pharmacological actions ... -
Methylene blue analogues with marginal monoamine oxidase inhibition retain antidepressant-like activity
(ACS, 2018)Methylene blue (MB) possesses diverse medical applications. Among these, MB presents with antidepressant-like effects in animals and has shown promise in clinical trials for the treatment of mood disorders. As an antidepressant, ...