Browsing by Subject "Chitosan"
Now showing items 1-10 of 20
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Characterization of the flow and compression properties of chitosan
(North-West University, 2008)The most useful dosage form taken from a patient's point of view is tablets because of its simplicity and portability (Takeuchi et al., 2004:132). Manufacturing of tablets can be done by wet granulation or direct compression ... -
A comparison on the release modifying behaviour of chitosan and kollidon SR
(North-West University, 2007)Controlled release formulations deliver an active ingredient over an extended period of time. It is an ideal dosage form for an active ingredient with a short elimination half-life. An active ingredient with a short ... -
Development and evaluation of a double-phase multiple-unit dosage form for enhanced insulin intestinal delivery
(Bentham Science, 2018)Background: The oral route is the most preferred route of administration for selfmedication, but poor membrane permeability and pre-systemic degradation are key challenges that need to be addressed. Objective: The purpose ... -
Development of a biodegradable biopolymer from renewable natural resources suitable for additive manufacturing and bone tissue engineering
(North-West University (South Africa), 2020)Bone tissue engineering scaffolds fabricated by additive manufacturing can offer an alternative treatment option to currently used bone graft methodologies. Chitosan, a biocompatible and biodegradable naturally derived ... -
Development of a double phase dosage form for enhanced peptide drug delivery
(2015)Parenteral administration remains the most utilised route of administration for therapeutic peptides due to low intestinal epithelial permeability. However, the most convenient and popular route of drug administration ... -
Direct compression of chitosan: process and formulation factors to improve powder flow and tablet performance
(Bentham Science, 2013)Chitosan is a polymer derived from chitin that is widely available at relatively low cost, but due to compression challenges it has limited application for the production of direct compression tablets. The aim of this study ... -
The effect of pharmaceutical excipients on isoniazid release from chitosan beads
(North-West University, 2007)In controlled release applications a drug is molecularly dispersed in a polymer phase. In the presence of a thermodynamically compatible solvent, swelling occurs and the polymer releases its content to the surrounding ... -
The effect of pharmaceutical excipients on rifampicin release from chitosan beads
(North-West University, 2004)Controlled release systems aim at achieving a predictable and reproducible drug release over a desired time period. These systems allow reduced dosing frequency, constant drug levels in the blood, increased patient compliance ... -
The effect of pharmaceutical excipients on the release of indomethacin from chitosan beads
(North-West University, 2006)Chitosan has proven through the years as a versatile biomaterial to be used in pharmaceutical applications. Its mucoadhesive properties as well as its ability to manipulate the tight junctions in epithelium membranes have ... -
Formulation of a chitosan multi-unit dosage form for drug delivery to the colon
(North-West University, 2006)In some diseases it is preferable that the drugs used in their treatment are released in the colon. The colon is also suitable for systemic delivery of a variety of drugs. A variety of systems have been developed for the ...