Browsing by Subject "Hemodynamics"
Now showing items 1-2 of 2
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Cardiovascular safety pharmacology studies in dogs enabled for a poorly soluble molecule using spray-dried dispersion: impact on lead selection
(Elsevier, 2016)The aim of this study was to identify an adequate formulation for a poorly soluble lead molecule (BI-A) that would achieve sufficiently high plasma concentrations after oral administration in dogs to enable a robust ... -
Marinobufagenin and its relationship with systolic blood pressure in a young black and white population : the African-PREDICT study
(North-West University (South Africa) , Potchefstroom Campus, 2016)Motivation: Hypertension remains one of the foremost causes of cardiovascular morbidity and mortality in sub-Saharan Africa. Importantly, the prevalence of hypertension within black and white populations has been ascribed ...