Browsing by Subject "In vitro"
Now showing items 1-10 of 10
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The effects of fungal strains with biocontrol potential on the motility and reproduction of Meloidogyne incognita
(North-West University (South Africa), 2023)Root-knot nematodes (Meloidogyne spp.) pose a global threat to grain crop production since it causes major yield losses which results in less food sources for animals and humans. Since classical nematicides are continually ... -
Evaluation of the effect of colloidal systems on biodistribution of selected prostate cancer radiopharmaceuticals
(North-West University (South-Africa), 2019)It has been reported that microemulsion (ME) delivery systems provide an opportunity to enhance the bioavailability and efficacy of a therapeutic agent whilst minimising side effects. The prostate-specific membrane antigen ... -
Formulation and topical delivery of niosomes and proniosomes containing carnosine
(North-West University (South Africa) , Potchefstroom Campus, 2016)Wiechers (2008:1-18) explains that the efficacy of a biologically active cosmetic product depends on both the intrinsic activity of the active, as well as the delivery of the active. This study aimed to deliver the ... -
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid
(Elsevier, 2013)Poly-(dl-lactic-co-glycolic) acid (PLGA) nanoparticles were prepared by a double emulsion solvent evaporation spray-drying technique and coated with polyethylene glycol (PEG 1% v/v). The PLGA nanoparticles had a small ... -
In-vitro transdermal penetration of cytarabine and its N4-alkylamide derivatives
(Wiley, 2010)Objectives The aim of this study was to synthesise and determine the transdermal penetration of cytarabine alkylamide derivatives and assess the correlation of flux with physicochemical properties. Methods The alkylamide ... -
Inhibitory effects of novel ciprofloxacin derivatives on the growth of four Babesia species and Theileria equi
(Springer, 2020)The problems of parasite resistance, as well as the toxic residues to most of the commercially available antipiroplasmic drugs severely weaken their effective, curative, and environmental safe employment. Therefore, it is ... -
Investigations on the respiratory effects of ozone in the rodent
(North-West University, 2010)Ozone, being an unstable molecule, is believed to be one of the strongest oxidant agents known to man. Rapid growth in the application of ozone — both as disinfectant and as form of alternative medicine — led to questions ... -
Preclinical assessment of 68Ga‐PSMA‐617 entrapped in a microemulsion delivery system for applications in prostate cancer PET/CT imaging
(Wiley, 2019)It has in recent years been reported that microemulsion (ME) delivery systems provide an opportunity to improve the efficacy of a therapeutic agent whilst minimising side effects and also offer the advantage of favourable ... -
Synthesis and in vitro antileishmanial efficacy of benzyl analogues of nifuroxazide
(Wiley, 2020)Leishmaniasis is a vector‐borne parasitic disease that mostly affects populations in tropical and subtropical countries. There is currently no vaccine to protect against and only a handful of drugs are available to treat ... -
Transdermal diffusion stability and clinical efficacy of cosmetic formulations containing Rosa rubiginosa rosehip seed oil
(North-West University (South Africa) , Potchefstroom Campus, 2016)This study aimed at investigating cosmeceutical product development from concept to clinical efficacy testing, using Rosa rubiginosa rosehip seed oil, sourced from Southern African soil. Rosehip seed oil contains various ...