Browsing by Subject "Methamphetamine"
Now showing items 1-6 of 6
-
Effects of early-life administration of methamphetamine on the depressive-like behaviour later in life in stress-sensitive and control rats
(2013)Methamphetamine (MA) is a well-known, easily accessible and powerful psychostimulant, and its abuse has become a global problem. MA abuse affects millions of people worldwide and places an enormous burden on public healthcare ... -
An investigation into the effects of Sceletium tortuosum in a methamphetamine addiction model in Sprague Dawley rats
(North-West University (South-Africa), 2021)Background: Methamphetamine (MA), globally known as “crystal meth”, is a highly addictive psychostimulant, which can be easily synthesized by using over the counter medicine and common household items. It induces intense ... -
The long-term effects of methamphetamine exposure during pre-adolescence on depressive-like behaviour in a genetic animal model of depression
(Springer, 2016)Methamphetamine (METH) is a psychostimulant and drug of abuse, commonly used early in life, including in childhood and adolescence. Adverse effects include psychosis, anxiety and mood disorders, as well as increased risk ... -
The long-term effects of methamphetamine on depressive-like behaviour and neuroplasticity in stress-sensitive rats
(2014)Methamphetamine (METH) abuse has become a fast growing drug problem that has developed into a global epidemic. In fact, METH is one of the most commonly abused substances with an estimated 35 million abusers worldwide and ... -
N-acetyl cysteine reverses bio-behavioural changes induced by prenatal inflammation, adolescent methamphetamine exposure and combined challenges
(Springer, 2018)Rationale Schizophrenia is associated with prenatal inflammation and/or postnatal stressors such as drug abuse, resulting in immune-redox dysfunction. Antioxidants may offer therapeutic benefits. Objectives The objective ... -
Studies on N-acetyl cysteine as a therapeutic intervention in methamphetamine-associated bio-behavioural changes in an immune-inflammatory model
(2015)Purpose: Schizophrenia is a severe illness, affecting 0.5-1% of the world population. The clinical manifestation of schizophrenia is characterized by three distinct categories of symptoms, namely positive, negative and ...