Browsing by Subject "Natural products"

Now showing items 1-4 of 4

    • An investigation of plant derived compounds as inhibitors of monoamine oxidase 

      Prinsloo, Denise (North-West University (South-Africa). Potchefstroom Campus, 2019)
      Computational chemistry, among other things, elucidates possible drug-molecular target interactions when an algorithm is run on a molecular modelling program. Although it is just a projection of reality, it enables researchers ...

    • MAO inhibitors and their wider applications: a patent review 

      Carradori, Simone; Petzer, Jacques P.; Secci, Daniela (Taylor & Francis, 2018)
      Introduction: Monoamine oxidase (MAO) inhibitors, after the initial ‘golden age’, are currently used as third-line antidepressants (selective MAO-A inhibitors) or clinically enrolled as co-adjuvants for neurodegenerative ...

    • Metathesis access to monocyclic iminocyclitol-based therapeutic agents 

      Dragutan, Ileana; Vosloo, Hermanus C.M.; Delaude, Lionel; Dragutan, Valerian; Mitan, Carmen (Beilstein-Institut, 2011)
      By focusing on recent developments on natural and non-natural azasugars (iminocyclitols), this review bolsters the case for the role of olefin metathesis reactions (RCM, CM) as key transformations in the multistep syntheses ...

    • Novel monoamine oxidase inhibitors: a patent review (2012-2014) 

      Carradori, Simone; Petzer, Jacobus P. (Taylor & Francis, 2015)
      Introduction: Monoamine oxidase (MAO) inhibitors, despite the initial pharmacological interest, are used in clinic for their antidepressant effect and in the management of Parkinson symptoms, due to the established ...