Now showing items 1-2 of 2

    • 6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity 

      Beteck, Richard M.; Van der Kooy, Frank; Legoabe, Lesetja J.; Jordaan, Audrey; Swart, Tarryn (Wiley, 2020)
      In this study, we synthesized novel nitro quinolone‐based compounds and tested them in vitro against a panel of Gram‐positive and Gram‐negative pathogens including Mycobacterium tuberculosis (MTB), Pseudomonas aeruginosa ...
    • Synthesis and in vitro anti-tubercular evaluation of 6-nitroquinolone-3-carboxamides 

      Dube, P.S. (North-West University (South Africa), 2020)
      Tuberculosis (TB) is a disease that has been a major scourge of humankind since time immemorial. It is an airborne disease that mainly affects the lungs and it is caused by Mycobacterium tuberculosis (Mtb)─ a pathogenic ...