Browsing by Subject "Transcriptomics"
Now showing items 1-4 of 4
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Effects of the organochlorine p,p’-DDT on MCF-7 cells: investigating metabolic and immune modulatory transcriptomic changes
(Elsevier, 2019)The organochlorine pesticide dichloro-diphenyl-trichloroethane (DDT) is persistent in the environment and leadsto adverse human health effects. High levels in breast milk pose a threat to both breast tissue and nursing ... -
The genome of a subterrestrial nematode reveals adaptations to heat
(Springer, 2019)The nematode Halicephalobus mephisto was originally discovered inhabiting a deep terrestrial aquifer 1.3 km underground. H. mephisto can thrive under conditions of abiotic stress including heat and minimal oxygen, where ... -
Investigating the adaptive mitochondrial shuttles and metabolic reprogramming of transporters in complex I (Ndufs4) knockout mice
(North-West University (South Africa), 2022)Mitochondrial disease is one of the most prevalent inherited paediatric disorders among children, with a prevalence of 1 in 5000 children. Leigh syndrome is the result of a Complex I (CI) deficiency and disrupts the redox ... -
Using “omics” and integrated multi-omics approaches to guide probiotic selection to mitigate chytridiomycosis and other emerging infectious diseases
(Frontiers Media, 2016)Emerging infectious diseases in wildlife are responsible for massive population declines. In amphibians, chytridiomycosis caused by Batrachochytrium dendrobatidis, Bd, has severely affected many amphibian populations and ...