Browsing by Subject "Transdermal"
Now showing items 1-10 of 12
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Development of topical/transdermal self-emulsifying drug delivery systems, not as simple as expected
(MDPI, 2020)Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs. However, the revolutionary drug delivery ... -
The effect of selected natural oils on the permeation of flurbiprofen through human skin
(North-West University, 2012)In pharmaceutical sciences, topical delivery is a transport process of an active pharmaceutical ingredient (API) from a formulated dosage form to the target site of action. For most topical delivery systems, the skin ... -
Essential fatty acids as transdermal penetration enhancers
(Elsevier, 2016)The aim of this study was to investigate the effect of different penetration enhancers, containing essential fatty acids (EFAs), on the transdermal delivery of flurbiprofen. Evening primrose oil (EPO), vitamin F and Pheroid™ ... -
Formulation, characterisation and topical delivery of salicylic acid containing whey–protein stabilised emulsions
(2014)Emulsions are widely used as topical formulations in the pharmaceutical and cosmetic industry. They are thermodynamically unstable and require emulsifiers to stabilize them physically. A literature survey has revealed that ... -
The implementation of the delivery gap principle to develop an effective transdermal delivery system for caffeine
(2013)Caffeine is frequently used in cosmetics due to its well-characterised skin permeation properties and is widely incorporated in cosmetic-related products intended for skin (Samah & Heard, 2013:631). Despite its polar ... -
Penetration enhancing effects of selected natural oils utilized in topical dosage forms
(Taylor & Francis, 2015)Context: Various natural products, including oils, have been utilized as penetration enhancers due to their “safety profiles”. These oils contain fatty acids promoting skin permeability through lipid fluidization within ... -
Topical delivery of clofazimine, artemisone and decoquinate utilizing vesicles as carrier system
(North-West University (South Africa), Potchefstroom Campus, 2018)Artemisone, clofazimine and decoquinate are part of the MALTBRedox MRC South African University Flagship Projects, which focus on oxidant-redox drug combinations for the treatment of tuberculosis and a few other diseases. ... -
The transdermal absorption of drugs that are suitable for use against morning sickness during pregnancy
(North-West University (South Africa), 1997)THE TRANSDERMAL ABSORPTION OF DRUGS THAT ARE SUITABLE FOR USE AGAINST MORNING SICKNESS DURING PREGNANCY The aim of this study was to determine the transdermal absorption of appropriate antiemetic drugs for use during ... -
Transdermal delivery of 5-Fluorouracil with PheroidTM technology
(North-West University, 2008)5-Fluorouracil (5FU) is a pyrimidine analogue, indicated for the therapy of proliferative skin diseases such as actinic keratosis (AK), superficial basal cell carcinoma and psoriasis. It has also been used for the treatment ... -
The use of grapeseed oil emulsions for the transdermal delivery of selected statins
(North-West University (South-Africa), 2020)Statins are used for the medical treatment of hypercholesterolemia, but after oral administration, it may cause gastro-intestinal disturbances and first-pass hepatic metabolism may decrease the bioavailability. Hence, the ...