Browsing by Author "13152726 - Peters, Dimetrie Leslie"
Now showing items 1-4 of 4
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Continuous adaptation through genetic communication: a putative role for cell-free DNA
Peters, Dimetrie L.; Pretorius, Piet J. (Taylor & Francis, 2012)Introduction: The virtosome fraction of cell-free DNA, being newly synthesised, capable of horizontal gene transfer (HGT) and subsequent genomic incorporation and expression, may play crucial roles in the biological functions ... -
Kinetic analysis, size profiling, and bioenergetic association of DNA released by selected cell lines in vitro
Aucamp, Janine; Bronkhorst, Abel J.; Peters, Dimetrie L.; Van Dyk, Hayley C.; Van der Westhuizen, Francois H.; Pretorius, Piet J. (Springer, 2017)Although circulating DNA (cirDNA) analysis shows great promise as a screening tool for a wide range of pathologies, numerous stumbling blocks hinder the rapid translation of research to clinical practice. This is related ... -
Origin, translocation and destination of extracellular occurring DNA: a new paradigm in genetic behaviour
Peters, Dimetrie L.; Pretorius, Piet J. (Elsevier, 2011)The diagnostic value of extracellular occurring DNA (eoDNA) is limited by our lack of understanding its biological function. eoDNA exists in a number of forms, namely vesicle bound DNA (apoptotic bodies, micro particles, ... -
Sequence analysis of cell-free DNA derived from cultured human bone osteosarcoma (143B) cells
Bronkhorst, Abel Jacobus; Wentzel, Johannes F.; Peters, Dimetrie L.; Aucamp, Janine; Pretorius, Piet J. (Sage, 2018)The true importance of cell-free DNA in human biology, together with the potential scale of its clinical utility, is tarnished by a lack of understanding of its composition and origin. In investigating the cell-free DNA ...