Now showing items 1-4 of 4

    • Amorphism and polymorphism of azithromycin 

      Odendaal, Roelf Willem (North-West University, 2012)
      Azithromycin, an azalide and member of the macrolide group, is a broad spectrum antimicrobial, representing one of the bestselling antimicrobials worldwide. It is derived from erythromycin and exhibits improved acidic ...
    • In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum 

      Du Plessis, Lissinda H.; Van Niekerk, Anel C.; Maritz, Marlene M.; Kotzé, Awie F. (Nature Publishing Group, 2012)
      The macrolide antibiotics, erythromycin and azithromycin, have been studied for their potential antimalarial activity, but only modest activity has been demonstrated. In this study, we investigated the enhancement of the ...
    • In vitro antimalarial efficacy enhancement of selected antibiotics with PheroidTM technology 

      Van Niekerk, Elizabeth Catharina (North-West University, 2010)
      The Plasmodium falciparum parasite, carried by Anopheles mosquitoes, is currently a global problem due to the rising incidence of resistance of the parasite to available antimalaria drugs. Resistance and difficult treatment ...
    • Stability of amorphous azithromycin in a tablet formulation 

      Obulapuram, Prasanna Kumar (2014)
      It is a well-known fact that drugs can exist in different solid-state forms. These solid-state forms can be either crystalline or amorphous. Furthermore, significant differences are identified between the different solid-state ...