Browsing by Author "Booysen, Laetitia"
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Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration
Semete, Boitumelo; Booysen, Laetitia; Kalombo, Lonji; Ramalapa, Bathabile; Hayeshi, Rose; Swai, Hulda S. (Elsevier, 2012)The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ... -
In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems
Semete, Boitumelo; Booysen, Laetitia; Lemmer, Yolandy; Kalombo, Lonji; Katata, Lebogang; Verschoor, Jan; Swai, Hulda S. (Elsevier, 2010)The remarkable physicochemical properties of particles in the nanometer range have been proven to address many challenges in the field of science. However, the possible toxic effects of these particles have raised some ...