Browsing by Subject "Chalcones"
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Antioxidant Properties of Kanakugiol Revealed Through the Hydrogen Atom Transfer, Electron Transfer and M2+ (M2+=Cu(II) or Co(II) Ion) Coordination Ability Mechanisms. A DFT Study In Vacuo and in Solution
(Springer Verlag, 2015)DFT studies on the conformational and antioxidant properties of kanakugiol were performed to investigate factors that contribute to its conformational preferences and to elucidate its antioxidant properties and mechanisms. ... -
In vitro anti-trypanosomal activities of indanone-based chalcones
(Thieme, 2019)Human African trypanosomiasis is a neglected infectious disease that affects mostly people living in the rural areas of Africa. Current treatment options are limited to just four drugs that have been in use of four to nine ... -
Monoamine oxidase inhibitory activities of heterocyclic chalcones
(2013)Parkinson’s disease is the second most common age-related neurodegenerative disease after Alzheimer’s disease. The characteristic pathological feature of Parkinson’s disease is the loss of neurons in the substantia nigra ... -
Syntheses of chalcones and 2–aminopyrimidines and their evaluation as monoamine oxidase inhibitors and as adenosine receptor antagonists
(North-West University, 2013)Background and rationale - Parkinson’s disease is a neurodegenerative disorder characterised by reduced levels of dopamine in the brain. The cause of Parkinson's disease is still unknown; however several theories pertaining ... -
Synthesis and evaluation of cyclic chalcones as monoamine oxidase inhibitors
(North-West University (South Africa) , Potchefstroom Campus, 2016)Parkinson’s disease (PD) is the second most-prevalent age-related neurodegenerative disorder following Alzheimer’s disease. The manifestation of clinical PD begins after a loss of neurons from the substantia nigra pars ...