Browsing by Subject "Cytotoxicity"
Now showing items 1-10 of 34
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Alternaria toxins in South African sunflower seeds: cooperative study
(Springer, 2017)Sunflower seed samples (N = 80) from different sunflower cultivars originating from different localities in South Africa were analyzed for 15 toxins produced by fungi of the genus Alternaria by means of a simple one-step ... -
Antimalarial activity of 10-alkyl/aryl esters and – aminoethylethers of artemisinin
(Elsevier, 2013)A series of n-alkyl/aryl esters were synthesized and their in vitro antiplasmodial activity was measured alongside that of previously synthesized aminoethylethers of artemisinin ozonides against various strains of ... -
Antimicrobial activity and in vitro cytotoxicity of selected South African Helichrysum species
(Elsevier, 2011)The antimicrobial activity of 35 indigenous South African Helichrysum species was determined against six microorganisms. Seven of the 36 chloroform:methanol (1:1) extracts (leaf and stem extracts for all plants and an ... -
The antioxidant properties, cytotoxicity and monoamine oxidase inhibition abilities of the crude dichloromethane extract of Tarchonanthus camphoratus L. leaves
(Academic Journals, 2011)Tarchonanthus camphoratus (camphor bush) has been widely used for numerous medicinal purposes. The aim of the present study was to evaluate the antioxidant properties, cytotoxicity and monoamine oxidase inhibition activities ... -
Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration
(Oxford Univ Press, 2019)Objectives Drug resistance exists to all current and investigational antimalarial drug classes. Consequently, we have set out to develop chemically and mechanistically discrete antimalarials. Here we report on the development ... -
The genotoxic effect of gold nanoparticles in cultured human cells
(North-West University (South Africa), 2016)Gold nanoparticles are ultrafine particles which are being used diversely in the medical field. Despite their versatility, the toxicity research which has been conducted on these particles is incredibly limited as well ... -
In vitro antioxidant, antimutagenic and genoprotective activity of Rosa roxburghii fruit extract
(Wiley, 2008)The antioxidant properties of the fruit of the Rosa roxburghii (RR) plant have been associated with several putative health promoting effects. The possible cytotoxic, mutagenic/antimutagenic and genotoxic effects of RR ... -
In vitro cytotoxicity of Siphonochilus aethiopicus in combination with selected fillers for tableting
(North-West University, 2018)The use of herbal medicines is currently experiencing a revival of sorts. However, this resurgence in popularity is casting a much needed light on safety issues relevant to the use thereof, since many herbal products remain ... -
In vitro determination of the endocrine disrupting capacity of microplastics
(North-West University (South Africa), 2022)Since the development of plastic in the early 20th century, it has become essential in day-to-day living. The demand for plastic has grown exponentially to a point where there are over 300 million tonnes of plastic produced ... -
In vitro efficacy of cations incorporated in Absorbatox® for wound healing
(North-West University (South-Africa), 2020)Wound healing can be described as a cascade of cells activated to restore tissue integrity, in order to regain the body’s natural function. Wound care plays a pivotal role in achieving therapeutic outcomes in wounds to ...