Now showing items 1-5 of 5

    • A gene-environment study of cytoglobin in the human and rat hippocampus 

      Hundahl, Christian Ansgar; Elfving, Betina; Müller, Heidi Kaastrup; Hay-Schmidt, Anders; Wegener, Gregers (Public Library of Science, 2013)
      Background: Cytoglobin (Cygb) was discovered a decade ago as the fourth vertebrate heme-globin. The function of Cygb is still unknown, but accumulating evidence from in vitro studies point to a putative role in scavenging ...
    • A gene–environment study of cytoglobin in the human and rat hippocampus 

      Hundahl, Christian Ansgar; Wegener, Gregers; Elfving, Betina; Müller, Heidi Kaastrup; Hay-Schmidt, Anders (Public Library of Science, 2013)
      Background: Cytoglobin (Cygb) was discovered a decade ago as the fourth vertebrate heme-globin. The function of Cygb is still unknown, but accumulating evidence from in vitro studies point to a putative role in scavenging ...
    • An inhibitor of cAMP-dependent protein kinase induces behavioural and neurological antidepressant-like effects in rats 

      Brink, Christiaan Beyers; Elfving, Betina; Fischer, Christina; Harvey, Brian Herbert; Liebenberg, Nico; Wegener, Gregers; Müller, Heidi Kaastrup (Elsevier, 2011)
      Although it is well established that cyclic adenosine monophosphate (cAMP) signalling via cAMPdependent protein kinase (PKA)within neurons plays an important role in depression and antidepressant treatment, the importance ...
    • Isolation-induced behavioural changes in a genetic animal model of depression 

      Fischer, Christina W.; Wegener, Gregers; Liebenberg, Nico; Elfving, Betina; Lund, Sten (Elsevier, 2012)
      Depression is a heterogeneous disorder displaying a range of symptoms including feelings of despair and social withdrawal. Social isolation may complicate the progression of depression and have effects on both behaviour ...
    • The schizophrenia and bipolar disorder associated BRD1 gene is regulated upon chronic restraint stress 

      Christensen, Jane; Elfving, Betina; Muller, Heidi; Wegener, Gregers; Fryland, Tue (Elsevier, 2012)
      Recent genetic evidence has implicated the bromodomain containing 1 gene (BRD1) with brain development and susceptibility to Schizophrenia and Bipolar Disorder. The BRD1 protein, which is essential for acetylation of histone ...