Now showing items 1-2 of 2

    • The synthesis and transdermal delivery of stavudine derivatives 

      Holmes, Estée-Marie (North-West University, 2006)
      The skin is an amazingly flexible and relatively impermeable barrier that provides protective, perceptive and communication functions to the human body. The interest in transdermal drug delivery may be attributed to the ...
    • Synthesis and transdermal penetration of stavudine-5'-esters. 

      Holmes, Estée-Marie; Breytenbach, Jaco C.; Gerber, Minja; Du Plessis, Jeanetta (Bentham Science Publishers, 2010)
      The aim of this study was to investigate the effects of different ester groups in position 5’ of stavudine on the transdermal penetration with and without the use of Pheroid™ as the delivery system. Six esters were prepared ...