The evolution of aerobic metabolic processes unavoidably led to the production of reactive
oxygen species (ROS). ROS have the ability to cause harmful oxidative damage to
biomolecules. Increased ROS generation and subsequent ...
Compromised calcium homeostasis in the central nervous system (CNS) is implicated as a major contributor in the pathology of neurodegeneration. Dysregulation of Ca2+ homeostasis initiates downstream Ca2+–dependent events ...