Browsing by Author "Otto, A."
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Effect of emulsifiers and their liquid crystalline structures in emulsions on dermal and transdermal delivery of hydroquinone, salicylic acid and octadecenedioic acid
Otto, A.; Hadgraft, J.; Du Plessis, J.; Wiechers, J.W.; Kelly, C.L. (Karger, 2010)This study investigated the effect of emulsifiers and their liquid crystalline structures on the dermal and transdermal delivery of hydroquinone (HQ), salicylic acid (SA) and octadecenedioic acid (DIOIC). Emulsions containing ... -
Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients
Otto, A.; Hadgraft, J.; Du Plessis, J.; Wiechers, J.W.; Kelly, C.L. (Karger, 2008)In this study the effect of 2 penetration modifiers, dimethyl isosorbide (DMI) and diethylene glycol monoethyl ether (DGME) on the skin delivery of hydroquinone (HQ), salicylic acid (SA) and octadecenedioic acid (DIOIC) ... -
Formulation effects of topical emulsions on transdermal and dermal delivery
Otto, A.; Du Plessis, J.; Wiechers, J.W. (Wiley, 2009)It has been recognized that the vehicle in which a permeant is applied to the skin has a distinctive effect on the dermal and transdermal delivery of active ingredients. The cutaneous and percutaneous absorptions can be ... -
Formulation, characterisation and topical application of oil powders from whey protein stabilised emulsions
Kotze, Magdalena (2014)The available literature indicates that to date, few research has been performed on oil powders for topical delivery. The aim of this project was to investigate the release characteristics of oil powder formulations, as ... -
Formulation, characterisation and topical delivery of salicylic acid containing whey–protein stabilised emulsions
Combrinck, Johann (2014)Emulsions are widely used as topical formulations in the pharmaceutical and cosmetic industry. They are thermodynamically unstable and require emulsifiers to stabilize them physically. A literature survey has revealed that ...