Browsing by Author "Pheiffer, Wihan"
Now showing items 1-6 of 6
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Evaluation of the in vitro biocompatibility of cortical bone matrix
Olivier, Charl (North-West University (South-Africa), 2022)Bone grafts play a critical role in the medical field, providing people the opportunity to recover from high impact trauma that caused serious complex fractures. Bone tissue engineering is a field that gained great interest ... -
Investigating morphological changes in fish tissue, due to the presence of persistent organic pollutants and metals
Pheiffer, Wihan (North-West University, 2012)Levels of selected metals and persistent organic pollutants (POPs) were investigated in sediment and fillet tissue of the sharptooth catfish (Clarias gariepinus), from sites along the Orange-Vaal River system, South Africa. ... -
Polycyclic aromatic hydrocarbons (PAHs) in the aquatic ecosystems of Soweto and Lenasia
Pheiffer, Wihan (North-West University (South Africa), Potchefstroom Campus, 2017)In South Africa, our scarce water resources are fully utilised and its quality threatened by pollution and therefore must be protected. One of the pollutant classes of concern is the polycyclic aromatic hydrocarbons (PAHs). ... -
The safety and efficacy of Meriva (R) and ginger extract combination in Pheroid (R) against lung cancer
Bekele, Bisrat; Pheiffer, Wihan; Grobler, Anne F. (Elsevier, 2020)Lung cancer is the leading cause of cancer related deaths, globally, with poor survival profile. Cisplatin is frequently used in the treatment of many solid tumors including lung cancer despite its toxicity; ototoxicity, ... -
The use of cytokines and oxidative stress markers as indicators for drug safety
Griessel, Helene; Pheiffer, Wihan; Jansen van Rensburg, Emile; Zeevaart, Jan Rijn; Grobler, Anne F. (Elsevier, 2020)Safety and efficacy are of concern in developing new compounds. There is a paucity on the changes made by new compounds on inflammatory cytokines in combination with oxidative stress markers. Cytokines are potential markers ... -
The use of cytokines as indicators for drug safety
Griessel, Helene; Pheiffer, Wihan; Du Plessis, Jesslee; Grobler, Anne Frederica; Zeevaart, Jan-Rijn (Elsevier, 2019)In developing new compounds, questions about safety and efficacy are raised. Conventional preclinical studies of new compounds focus on bio-distribution, toxicology, safety pharmacology, pharmacokinetics, efficacy etc., ...