Now showing items 1-2 of 2

    • A model of isoniazid treatment of tuberculosis 

      Lemmer, Yolandy; Grobler, Anne; Viljoen, Hendrik; Moody, Clint (Elsevier, 2014)
      A mathematical model is presented of the growth and death of bacilli in a granuloma. The granuloma is treated with isoniazid (INH), a drug that inhibits the synthesis of mycolic acids (MA). Since MA is an essential component ...
    • Rapid cell lysis and DNA capture in a lysis microreactor 

      Booth, Christine; Grobler, Anne Frederica; Levanets, Oskana; Viljoen, Hendrik; Whitney, Scott (Elsevier, 2012)
      In clinical diagnostics, the detection and identification of bacterial organisms based on the analysis of their nucleic acids require cell lysis and DNA extraction from clinical samples. A lysis microreactor (LMR) has been ...