Spectral, thermal stability and antibacterial studies of copper, nickel and cobalt complexes of N-methyl-N-phenyl dithiocarbamate
Date
2015Author
Ekennia, Anthony C.
Onwudiwe, Damian C.
Osowole, Aderoju A.
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Copper(II), cobalt(II) and nickel(II) bis(N-methyl-N-phenyl dithiocarbamate) complexes having the general
formula [M{S2CN(MePh)}2] (where M = Cu, Co and Ni) have been prepared and characterized
by spectral and thermal analysis. The IR spectra suggest that coordination of dithiocarbamate (DTC)
occurred through the two sulfur atoms in a symmetrical bidentate fashion. The electronic spectra, conductance
measurement and magnetic moment analysis support the proposed geometry for the electronically
dilute complexes. The results of the thermal analysis showed that after dehydration, a one-step decomposition
pattern leading to the formation of respective metal sulfide as the end-product occurred. The
results are consistent with the proposed composition of the complexes. The in vitro antibacterial activity
of the complexes was investigated against strains of gram-negative Escherichia coli, Klebsiella oxytoea
and Pseudomonas aureginosa, and gram-positive Bacillus cereus, Staphylococcus aureus and Protues
mirabilis. The antibacterial activity of the complexes compared favorably with that of streptomycin and
augmentine against S. aureus and B. cereus. The cobalt complex had the best antibacterial activity against
the test compounds with inhibitory zone range of 11–14.5 mm
URI
http://hdl.handle.net/10394/18495http://dx.doi.org/10.1080/17415993.2014.969731
http://www.tandfonline.com/doi/full/10.1080/17415993.2014.969731