Now showing items 1-5 of 5

    • Cutaneous tuberculosis overview and current treatment regimens 

      Van Zyl, Lindi; Du Plessis, Jeanetta; Viljoen, Joe (Elsevier, 2015)
      Tuberculosis is one of the oldest diseases known to humankind and it is currently a worldwide threat with 8e9 million new active disease being reported every year. Among patients with co-infection of the human immunodeficiency ...
    • In vitro skin permeation of sinigrin from its phytosome complex 

      Mazumder, Anisha; Dwivedi, Anupma; Fox, Lizelle T.; Brümmer, Alicia; Du Preez, Jan L.; Gerber, Minja; Du Plessis, Jeanetta (Wiley, 2016)
      Objectives: Sinigrin is a major glucosinolate present in plants of the Brassicaceae family. Recently sinigrin and its phytosome formulations have been investigated for its wound healing actions, by our research group. The ...
    • The influence of pH on the in vitro permeation of rhodium through human skin 

      Jansen van Rensburg, Sané; Franken, Anja; Du Plessis, Jeanetta; Du Plessis, Johannes Lodewykus (Sage, 2017)
      Workers in precious metals refineries are at risk of exposure to salt compounds of the platinum group metals through inhalation, as well as through the skin. Rhodium salt permeation through the skin has previously been ...
    • Topical delivery of artemisone, clofazimine and decoquinate encapsulated in vesicles and their in vitro efficacy against Mycobacterium tuberculosis 

      Van Zyl, Lindi; Viljoen, Joe M.; Haynes, Richard k.; Aucamp, Marique; Du Plessis, Jeanetta (Springer, 2019)
      Vesicles are widely investigated as carrier systems for active pharmaceutical ingredients (APIs). For topical delivery, they are especially effective since they create a “depot-effect” thereby concentrating the APIs in the ...
    • Traversing the skin barrier with nano-emulsions 

      Burger, Cornel; Shahzad, Yasser; Brümmer, Alicia; Gerber, Minja; Du Plessis, Jeanetta (Bentham Science, 2016)
      In recent years, colloidal delivery systems based on nano-emulsion are gaining popularity; being used for encapsulation and delivery of many drugs. Nano-emulsions are thermokinetically stable dispersion systems, which ...