Browsing Research Output by Author "cce5e9dd-52f0-44cb-9180-c4cec548946b"
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Development and validation of a LC-MS/MS method for the quantitation of lumefantrine in mouse whole blood and plasma
Govender, Katya; Du Plessis, Lissinda; Gibhard, Liezl; Wiesner, Lubbe (Elsevier, 2015)A liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed and validated for the quantitation of the antimalarial drug, lumefantrine (LF), in mouse whole blood and plasma. The analyte was extracted ... -
Intestinal drug absorption enhancement by Aloe vera gel and whole leaf extract: in vitro investigations into the mechanisms of action
Haasbroek, Anja; Willers, Clarissa; Glyn, Matthew; Du Plessis, Lissinda; Hamman, Josias (MDPI, 2019)The co-administration of absorption enhancing agents with macromolecular drugs (e.g., protein and peptide drugs) has been identified as a means to improve the oral bioavailability of these drugs. Absorption-enhancing agents ...