Browsing Research Output by Title
Now showing items 34-53 of 13384
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24-Hour central blood pressure: reference values for healthy individuals. The international 24hour ambulatory aortic blood pressure consortium (I24ABC)
(Wolters Kluwer, 2019)Objective: Central systolic blood pressure (cSBP) differs from peripheral SBP (pSBP) and may have higher prognostic relevance, but the normal values in ambulatory conditions are unknown. We present reference values for ... -
25 Years of research on global asphyxia in the immature rat brain
(Elsevier, 2017)Hypoxic-ischemic encephalopathy remains a common cause of brain damage in neonates. Preterm infants have additional complications, as prematurity by itself increases the risk of encephalopathy. Currently, therapy for this ... -
3-Amino alkylated indoles as corrosion inhibitors for mild steel in 1M HCl: experimental and theoretical studies
(Elsevier, 2016)The present study describes the influence of ring and ring size of three 3-amino alkylated indoles (AAIs) namely, N-((1H-indol-3-yl)(phenyl)methyl)-N-ethylethanamine (AAI-1), 3-(phenyl(pyrrolidin-1-yl)methyl)-1H-indole ... -
3-Coumaranone derivatives as inhibitors of monoamine oxidase
(Dove Press, 2015)The present study examines the monoamine oxidase (MAO) inhibitory properties of a series of 20 3-coumaranone [benzofuran-3(2H)-one] derivatives. The 3-coumaranone derivatives are structurally related to series of α-tetralone ... -
3-D Finite element method analysis of twin-armature permanent magnet motor with two degrees of mechanical freedom
(Springer, 2016)In this paper, the authors present a twin-armature rotary–linear permanent magnet (PM) motor. The stator consists of two armatures which generate two rotating magnetic fields and the rotor consists of two rigidly coupled ... -
A 3-methylcrotonyl-CoA carboxylase deficient human skin fibroblast transcriptome reveals underlying mitochondrial dysfunction and oxidative stress
(Elsevier, 2016)Isolated 3-methylcrotonyl-CoA carboxylase (MCC) deficiency is an autosomal recessive inherited metabolic disease of leucine catabolism with a highly variable phenotype. Apart from extensive mutation analyses of the MCCC1 ... -
3-Methylglutaconic aciduria: lessons from 50 genes and 977 patients
(Springer, 2013)Elevated urinary excretion of 3-methylglutaconic acid is considered rare in patients suspected of a metabolic disorder. In 3-methylglutaconyl-CoA hydratase deficiency (mutations in AUH), it derives from leucine degradation. ... -
3C 279 in outburst in 2015 june: a broadband sed study based on the integral detection
(IOP Publishing, 2016)Blazars radiate from radio through gamma-ray frequencies and thereby make ideal targets for multifrequency studies. Such studies allow the properties of the emitting jet to be constrained. 3C 279 is among the most notable ... -
3D analysis of synaptic vesicle density and distribution after acute foot‐shock stress by using serial section transmission electron microscopy
(Wiley, 2017)Behavioural stress has shown to strongly affect neurotransmission within the neocortex. In this study, we analysed the effect of an acute stress model on density and distribution of neurotransmitter‐containing vesicles ... -
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis
(Taylor & Francis, 2019)A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted ... -
5-Arylpyrimido-[4,5-b]quinoline-diones as new and sustainable corrosion inhibitors for mild steel in 1 M HCl: a combined experimental and theoretical approach
(Royal Society of Chemistry, 2016)The inhibition of mild steel corrosion in 1 M HCl by four 5-arylpyrimido-[4,5-b]quinoline-diones (APQDs), namely 5-(4-nitrophenyl)-5,10-dihydropyrimido [4,5-b]quinoline-2,4(1H,3H)-dione (APQD-1), 5-phenyl-5,10-dihydropyr ... -
5-Substituted 2-benzylidene-1-tetralone analogues as A1 and/or A2A antagonists for the potential treatment of neurological conditions
(Elsevier, 2017)Adenosine A1 and A2A receptors are attracting great interest as drug targets for their role in cognitive and motor deficits, respectively. Antagonism of both these adenosine receptors may offer therapeutic benefits in ... -
6-Nitro-1-benzylquinolones exhibiting specific antitubercular activity
(Wiley, 2020)In this study, we synthesized novel nitro quinolone‐based compounds and tested them in vitro against a panel of Gram‐positive and Gram‐negative pathogens including Mycobacterium tuberculosis (MTB), Pseudomonas aeruginosa ... -
6-phenylpyridazin-3(2H)one as new corrosion inhibitor for C38 Steel in 1 M HCl
(ESG, 2017)The corrosion behavior of C38 steel in HCl solutions and its inhibition by 6-phenylpyridazin-3(2H)one (PPO) has been studied in different temperature using polarization and electrochemical impedance spectroscopy (EIS) ... -
68Ga-NOTA-functionalized ubiquicidin: cytotoxicity, biodistribution, radiation dosimetry, and first-in-human PET/CT imaging of infections
(Society of Nuclear Medicine and Molecular Imaging, 2018)Ubiquicidin is an antimicrobial peptide with great potential for nuclear imaging of infectious diseases, as its cationic-rich fragment TGRAKRRMQYNRR (UBI) has been functionalized with NOTA to allow complexation to 68Ga ... -
The 72-h WEBT microvariability observation of blazar S5 0716+714 in 2009
(EDP Sciences, 2013)Context. The international Whole Earth Blazar Telescope (WEBT) consortium planned and carried out three days of intensive micro-variability observations of S5 0716+714 from February 22, 2009 to February 25, 2009. This ... -
8-(3-phenylpropyl)-1,3,7-triethylxanthine is a synthetic caffeine substitute with stronger metabolic modulator activity
(Elsevier, 2018)Caffeine is one of the most worldwide consumed methylxanthines. It is well-known for its thermogenic and cell metabolism modulating effects. Based on methylxanthines' chemical structure, 8-(3-phenylpropyl)-1,3,7-triethylxanthine ... -
8-Aryl- and alkyloxycaffeine analogues as inhibitors of monoamine oxidase
(Elsevier, 2011)Recently it was reported that a series of 8-benzyloxycaffeine analogues are potent reversible inhibitors of human monoamine oxidase (MAO) A and B. In an attempt to discover additional C8 oxy substituents of caffeine that ... -
8-Hydroxyquinoline as an Effective Corrosion Inhibitor for 7075 Aluminium Alloy in 3.5% NaCl Solution
(ESG, 2014)The inhibition of the corrosion of aluminium alloy in 3.5 wt.% NaCl solution by 8-hydroxyquinoline has been studied using electrochemical impedance spectroscopy (EIS), potentiodynamic polarization, scanning electrochemical ... -
8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
