Browsing Research Output by Subject "Comet assay"
Now showing items 1-6 of 6
-
Assessing the DNA methylation status of single cells with the comet assay
(Elsevier, 2010)The comet assay (single cell gel electrophoresis) is a cost-effective, sensitive, and simple technique that is traditionally used for analyzing and quantifying DNA damage in individual cells. The aim of this study was to ... -
DNA damage and repair detected by the comet assay in lymphocytes of African petrol attendants: a pilot study
(Oxford Univ Press, 2008)Petrol attendants are exposed to petrol volatile organic compounds (VOCs) which may have genotoxic and carcinogenic effects. The single-cell gel electrophoresis assay (comet assay) is a method highly sensitive to DNA damage ... -
Effect of biofumigants on soil microbial communities and ecotoxicology of earthworms (Eisenia andrei)
(Springer, 2016)Biofumigation is considered a good alternative to chemical fumigation because it can control crop pathogens and diseases with lower health and environmental risks than chemical fumigants. Glucosinolates are volatile compounds ... -
Hereditary tyrosinemia type 1 metabolites impair DNA excision repair pathways
(Elsevier, 2010)Hereditary tyrosinemia type 1 is an autosomal recessive metabolic disorder, which is caused by a defective fumarylacetoacetate hydrolase enzyme, and consequently metabolites such as succinylacetone and p-hydroxyphenylpyruvate ... -
Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatium
(Elsevier, 2008)We investigated the protective effect of pravastatin, simvastatin and atorvastatin on striatal DNA damage as a potential method to conserve and protect the nigrostriatal neurons. C57Bl/J6 mice were treated with combinations ... -
Ozone concentration dependant autohaemotherapy effects on baboon antioxidant capacity and DNA integrity and repair capacity of lymphocytes
(Academic Journals, 2009)Although ozone is widely used as an alternative medicine, its safety and efficiency are met with scepticism. To shed some light on this, we assessed the effect of ozone-autohaemotherapy, using an O2/O3 gas mixture ...