Browsing Research Output by Author "12850071 - Liebenberg, Leon"
Now showing items 1-20 of 22
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Can successful cancer therapies build on what we learn from complex disorders?
Mathews, Edward Henry; Liebenberg, Leon (Elsevier, 2012) -
Case study for evaluating benefits of pavement research: final results
Plessis, L.; Liebenberg, L.; Nokes, W.; Mahdavi, M.; Burmas, N.; Holland, T.; Harvey, J. (The National Academies of Sciences, Engineering, and Medicine, 2013)Heavy-duty pavement innovations developed through research for a major rehabilitation project in California were evaluated. The performance benefits of the innovations were examined, and the economic benefits from ... -
Case study: energy savings for a deep-mine water reticulation system
Vosloo, Jan; Liebenberg, Leon; Velleman, Douglas (Elsevier, 2012)In deep level mining, water reticulation systems are one of the major consumers of electricity. The refrigeration plants, together with the underground water supply and dewatering systems are integrated to form one complete ... -
Case study: the effects of a variable flow energy saving strategy on a deep-mine cooling system
Du Plessis, Gideon Edgar; Liebenberg, Leon; Mathews, Edward Henry (Elsevier, 2013)Cooling systems consume up to 25% of the total electricity used on deep level mines. These systems are integrated with the water reticulation system to provide chilled service water to the mine as well as cooling for mine ... -
Conversion of calcium sulphide to calcium carbonate during the process of recovery of elemental sulphur from gypsum waste
De Beer, M.; Liebenberg, L.; Maree, J.P.; Doucet, F.J. (Elsevier, 2014)The production of elemental sulphur and calcium carbonate (CaCO3) from gypsum waste can be achieved by thermally reducing the waste into calcium sulphide (CaS), which is then subjected to a direct aqueous carbonation step ... -
Does cancer risk increase with HbA1c, independent of diabetes?
De Beer, J.C.; Liebenberg, L. (Cancer Research UK, 2014)Background: The risks for several cancer types are increased in people with diabetes. Hyperglycaemia, hyperinsulinaemia, inflammation and altered hormonal concentrations are common characteristics between the two diseases ... -
Flow over a glider canopy
Jonker, A.S.; Bosman, J.J.; Mathews, E.H.; Liebenberg, L. (Royal Aeronautical Society, 2014)In order to minimise drag, the front part of most modern glider fuselages is shaped so that laminar flow is preserved to a position close to the wing-to-fuselage junction. Experimental investigations on a full-scale JS1 ... -
High-glycolytic cancers and their interplay with the body's glucose demand and supply cycle
Mathews, Edward Henry; Liebenberg, Leon; Pelzer, Ruaan (Elsevier, 2011)Many difficult-to-treat solid cancer tumours and metastases have high-glucose uptake, usually under hypoxic conditions. Hypoxic tumours suppress the immune system and are insensitive to traditional chemoradiotherapies. The ... -
How do high glycemic load diets influence coronary heart disease?
Mathews, Marc J.; Liebenberg, Leon; Mathews, Edward H. (BioMed Central, 2015)Background: Diet has a significant relationship with the risk of coronary heart disease (CHD). Traditionally the effect of diet on CHD was measured with the biomarker for low-density lipoprotein (LDL) cholesterol. However, ... -
Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines
Visagie, Michelle Helen; Liebenberg, Leon; Mathews, Edward Henry; Mathews, George Edward; Mqoco, Thandi Vuyelwa (BioMed Central, 2015)Background: Due to their high proliferative requirements, tumorigenic cells possess altered metabolic systems whereby cells utilize higher quantities of glutamine and glucose. These altered metabolic requirements make it ... -
Integrated energy optimisation for the cement industry: a case study perspective
Swanepoel, Jan Adriaan; Mathews, Edward Henry; Vosloo, Jan; Liebenberg, Leon (Elsevier, 2014)Energy costs play a major role in the cement production process. As much as 60% of total cost is allocated to energy and 18% to the consumption of electrical energy. Historically, energy cost savings were achieved by ... -
Load-shifting opportunities for typical cement plants
Lidbetter, Raine T.; Liebenberg, Leon (ERC (Energy Research Centre), 2013)Investigations into demand side reductions have been encouraged by the South African electricity utility, Eskom, in sectors with high electricity consumption, such as the cement industry. The South African cement ... -
The mechanism by which moderate alcohol consumption influences coronary heart disease
Mathews, Marc J.; Liebenberg, Leon; Mathews, Edward H. (BioMed Central, 2015)Background Moderate alcohol consumption is associated with a lower risk for coronary heart disease (CHD). A suitably integrated view of the CHD pathogenesis pathway will help to elucidate how moderate alcohol consumption ... -
The mechanisms by which antidepressants may reduce coronary heart disease risk
Mathews, Marc J.; Mathews, Edward H.; Liebenberg, Leon (BioMed Central, 2015)Background Depression is known to increase the risk for coronary heart disease (CHD) likely through various pathogenetic actions. Understanding the links between depression and CHD and the effects of mediating these links ... -
New gas nitriding technique using the interior of the nitrided pressure vessel as the process chamber
Nell, R.W.; Kleingeld, M.; Liebenberg, L. (SAIMM, 2016)The need to nitride the interior of large machine housings, which are also pressure vessels, for use in a high-temperature gas reactor resulted in the development of a suitable new nitriding technique whereby the ... -
On the wing density and the inflation factor of aircraft
Huyssen, R.J.; Mathews, E.H.; Liebenberg, L.; Spedding, G.R. (Royal Aeronautical Soc, 2016)The aviation industry is dominated by the domain of heavier-than-air, fixed-wing, subsonic flight, and central to any design in this domain is the wing itself. One of the earliest debates in aviation still centres around ... -
A simple demand-side management solution for a typical compressed-air system at a South African gold mine
Liebenberg, Leon; Velleman, Douglas; Booysen, Walter (ERC (Energy Research Centre), 2012)Once designed, mine compressed-air systems tend to operate at peak levels throughout the life of the mine, despite there being significant periods when this air quantity is not required. This is mainly due to lack of ... -
Synthesis of high-purity precipitated calcium carbonate during the process of recovery of elemental sulphur from gypsum waste
De Beer, M.; Liebenberg, L.; Doucet, F.J.; Maree, J.P. (Elsevier, 2015)We recently showed that the production of elemental sulphur and calcium carbonate (CaCO3) from gypsum waste by thermally reducing the waste into calcium sulphide (CaS) followed by its direct aqueous carbonation yielded ... -
The influence of timed coolant injection on compressor efficiency
Jacobs, G.G.; Liebenberg, L. (Elsevier, 2016)Timed injection of coolant during the onset of the compression stroke in a reciprocating compressor aimed at achieving quasi-isobaric conditions during the initial part of the compression stroke was investigated as a means ... -
Tumor cell culture survival following glucose and glutamine deprivation at typical physiological concentrations
Mathews, Edward Henry; Liebenberg, Leon; Stander, B. André; Joubert, Annie M. (Elsevier, 2014)Objective Most glucose (and glutamine)-deprivation studies of cancer cell cultures focus on total depletion, and are conducted over at least 24 h. It is difficult to extrapolate findings from such experiments to practical ...