Browsing Research Output by Subject "Gene expression"
Now showing items 1-7 of 7
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Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1
(Elsevier, 2012)The autosomal recessive disorder, hereditary tyrosinemia type 1 (HT1), is caused by a defective fumarylacetoacetate hydrolase enzyme. Consequently intermediate metabolites such as fumarylacetoacetate, succinylacetone and ... -
Iron and a mixture of DHA and EPA supplementation, alone and in combination, affect bioactive lipid signalling and morbidity of iron deficient South African school children in a two-by-two randomised controlled trial
(Elsevier Sci Ltd, 2016)We recently reported that iron supplementation increased respiratory morbidity in iron deficient South African children. This increase, however, was attenuated when iron was provided in combination with a mixture of DHA/EPA. ... -
Mitochondrial DNA replication and OXPHOS gene transcription show varied responsiveness to Rieske protein knockdown in 143B cells
(Elsevier, 2011)Genetic, biochemical and phenotypic diversity is a hallmark of OXPHOS deficiencies. Among the responses frequently reported for these deficiencies is differential expression of several genes involved in mitochondrial ... -
Oxidative stress biomarkers in the Mediterranean pond turtle (Mauremys leprosa) reveal contrasted aquatic environments in Southern France
(Elsevier, 2017)Increasing anthropogenic activities, like agricultural practices, constitute the main causes of the loss of water quality and disruption of freshwater ecosystems. High concentrations of pesticides, as shown under experimental ... -
Oxidative stress induced by glyphosate-based herbicide on freshwater turtles
(SETAC, 2017)Freshwater ecosystems face very strong anthropogenic pressures, among which overexploitation, habitat degradation, flow modification, species invasion, and water pollution lead to growing threats on biodiversity. Urbanization ... -
OXPHOS gene expression and control in mitochondrial disorders
(Elsevier, 2009)The cellular consequences of deficiencies of the mitochondrial OXPHOS system include a variety of direct and secondary changes in metabolite homeostasis, such as ROS, Ca2+, ADP/ATP, and NAD/NADH. The adaptive responses to ... -
A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex
(Elsevier, 2016)Ketamine is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that has been shown to induce a rapid antidepressant effect in treatment-resistant patients. Vortioxetine is a multimodal-acting antidepressant ...