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Browsing Research Output by Author "Gerber, Minja"

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Browsing Research Output by Author "Gerber, Minja"

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  • Shahzad, Yasser; Gerber, Minja; Du Plessis, Jeanetta; Khan, Ikram Ullah; Hussain, Talib; Alamgeer; Serra, Christophe A. (Bentham Science Publishers, 2014)
    Proteins are posed as the natural counterpart of the synthetic polymers for the development of drug delivery systems and few of them, have been regarded safe for drug delivery purposes by the United States Food and Drug ...
  • Shahzad, Yasser; Gerber, Minja; Du Plessis, Jeanetta; Khan, Ikram U.; Hussain, Talib (Bentham Science Publishers, 2014)
    Proteins are posed as the natural counterpart of the synthetic polymers for the development of drug delivery systems and few of them, have been regarded safe for drug delivery purposes by the United States Food and Drug ...
  • Shahzad, Yasser; Louw, Ruaan; Gerber, Minja; Du Plessis, Jeanetta (Elsevier, 2015)
    The impermeability of the stratum corneum often hinders the transport of molecules across the skin. Temperature modulations in the skin and the application of local heat both have the potential of circumventing this problem ...
  • Van Zyl, Lindi; Du Preez, Jan; Gerber, Minja; Du Plessis, Jeanetta; Viljoen, Joe (Wiley, 2015)
    The aim of this study was to investigate the effect of different penetration enhancers, containing essential fatty acids (EFAs), on the transdermal delivery of flurbiprofen. Evening primrose oil (EPO), vitamin F and Pheroid™ ...
  • Fox, Lizelle T; Du Plessis, Jeanetta; Gerber, Minja; Van Zyl, Sterna; Boneschans, Banie; Hamman, Josias H (Medknow Publications, 2014)
    Background: Although Aloe vera extracts have exhibited various effects on the skin, less is known about the biological activities of other aloe species on the skin. Objective: To investigate the skin hydrating and anti-erythema ...
  • Burger, Cornel; Gerber, Minja; Du Preez, Jan L.; Du Plessis, Jeanetta (Elsevier, 2015)
    Wiechers’ programme “Formulating for Efficacy” initiated a new strategy to optimise the oil phase of topical formulations in order to achieve optimal transdermal drug delivery. This new approach uses the “Delivery Gap ...
  • Viljoen, Joe M.; Cowley, Amé; Du Preez, Jan; Gerber, Minja; Du Plessis, Jeanetta (Taylor & Francis, 2015)
    Context: Various natural products, including oils, have been utilized as penetration enhancers due to their “safety profiles”. These oils contain fatty acids promoting skin permeability through lipid fluidization within ...
  • Chinembiri, Tawona N; Du Plessis, Lissinda H; Gerber, Minja; Hamman, Josias H; Du Plessis, Jeanetta (MDPI, 2014)
    Most anti-cancer drugs are derived from natural resources such as marine, microbial and botanical sources. Cutaneous malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. Various ...
  • Fox, Lizelle T.; Gerber, Minja; Du Preez, Jan L.; Du Plessis, Jeanetta; Hamman, Josias H. (Royal Pharmaceutical Society of Great Britain, 2015)
    Objectives: The aim of this study was to investigate the in vitro permeation enhancement effects of the gel and whole leaf materials of Aloe vera, Aloe marlothii and Aloe ferox using ketoprofen as a marker compound. Methods: ...
  • Gerber, Gezina S.F.W.; Fox, Lizelle T.; Gerber, Minja; Du Preez, Jan L.; Van Zyl, Sterna; Boneschans, Banie; Du Plessis, Jeanetta (Medknow Publications, 2015)
    Background: Honeybush extracts (Cyclopia spp.) can be incorporated into skin care products to treat conditions such as skin dryness and can function as an anti-oxidant. Objective: To formulate Honeybush formulations and ...
  • Breytenbach, Jaco Cornelius; Du Plessis, Jeanetta; Gerber, Minja; Holmes, Estee-marie (Bentham Science Publishers, 2010)
    The aim of this study was to investigate the effects of different ester groups in position 5 of stavudine on the transdermal penetration with and without the use of Pheroid™ as the delivery system. Six esters were prepared ...
  • Holmes, Estée-Marie; Breytenbach, Jaco C.; Gerber, Minja; Du Plessis, Jeanetta (Bentham Science Publishers, 2010)
    The aim of this study was to investigate the effects of different ester groups in position 5’ of stavudine on the transdermal penetration with and without the use of Pheroid™ as the delivery system. Six esters were prepared ...
  • Gerber, Minja; Breytenbach, Jaco C; Hadgraft, Jonathan; Du Plessis, Jeanetta (Elsevier, 2006)
    The primary aim of this study was to determine the transdermal penetration of acetylsalicylic acid and some of its derivatives, to establish a correlation, if any, with selected physicochemical properties and to determine ...
  • Fox, Lizelle Trifena; Gerber, Minja; Grobler, Anne Frederica; Du Preez, Jan Lourens; Du Plessis, Jeanetta (Karger, 2011)
    Background: The two types of skin aging (intrinsic and extrinsic) share important molecular features, while having distinct differences on the macromolecular level: both lead to increased production of reactive oxygen ...
  • Fox, Lizelle T.; Gerber, Minja; Du Preez, Jan L.; Grobler, Anne; Du Plessis, Jeanetta (Karger, 2011)
    Background: The two types of skin aging (intrinsic and extrinsic) share important molecular features, while having distinct differences on the macromolecular level: both lead to increased production of reactive oxygen ...
  • Chinembiri, Tawona N.; Gerber, Minja; Du Plessis, Lissinda; Du Preez, Jan L.; Du Plessis, Jeanetta (Springer Verlag, 2015)
    Drug delivery vehicles can influence the topical delivery and the efficacy of an active pharmaceutical ingredient (API). In this study the influence of Pheroid™ technology, which is a unique colloidal drug delivery system, ...
  • Jacobs, Gerda A.; Gerber, Minja; Malan, Maides M.; Du Preez, Jan L.; Fox, Lizelle T.; Du Plessis, Jeanetta (Taylor & Francis, 2014)
    Context: Viral and fungal cutaneous manifestations are regularly encountered in immunocompromised HIV/AIDS individuals and can be treated by drugs such as acyclovir and ketoconazole, respectively. Objective: The aim of ...
  • Fox, Lizelle T.; Gerber, Minja; Du Plessis, Jeanetta; Hamman, Josias H. (MDPI, 2011)
    The transdermal route of administration offers an alternative pathway for 20 systemic drug delivery with numerous advantages over conventional routes of 21 administration. Regrettably, the stratum corneum forms a formidable ...
  • Fox, Lizelle Trifena; Gerber, Minja; Hamman, Josias Hendrik; Du Plessis, Jeanetta (MDPI, 2011)
    The transdermal route of administration offers an alternative pathway for systemic drug delivery with numerous advantages over conventional routes. Regrettably, the stratum corneum forms a formidable barrier that hinders ...
  • Breytenbach, Jaco C; Du Plessis, Jeanetta; Gerber, Minja (Elsevier Science Limited, 2008)

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