Now showing items 1-2 of 2

    • Radiopharmaceutical enhancement by drug delivery systems: a review 

      Kleynhans, Janke; Grobler, Anne Frederica; Zeevaart, Jan Rijn; Ebenhan, Thomas; Sathekge, Mike Machaba (Elsevier, 2018)
      Introduction Drug delivery systems are entities designed to alter the biological behaviour of the pharmaceutical active ingredients that they carry in order to afford more beneficial biodistribution and safety profiles. ...
    • The use of cytokines as indicators for drug safety 

      Griessel, Helene; Pheiffer, Wihan; Du Plessis, Jesslee; Grobler, Anne Frederica; Zeevaart, Jan-Rijn (Elsevier, 2019)
      In developing new compounds, questions about safety and efficacy are raised. Conventional preclinical studies of new compounds focus on bio-distribution, toxicology, safety pharmacology, pharmacokinetics, efficacy etc., ...