Browsing Research Output by Author "Lategan, Carmen A."

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Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids

Lombard, Marli C.; N'Da, David D.; Breytenbach, Jaco C.; Smith, Peter J.; Lategan, Carmen A. (Elsevier, 2011)

Dihydroartemisinin (DHA) was coupled to different aminoquinoline moieties forming hybrids 9–14, which were then treated with oxalic acid to form oxalate salts (9a–14a). Compounds 9a, 10a, 12, 12a, and 14a showed comparable ...