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Browsing Research Output by Author "O'Neill, Hester Gertruida"

Now showing items 1-5 of 5

Characterization of domain-selective inhibitor binding in angiotensin-converting enzyme using a novel derivative of lisinopril

Kröger, Wendy; O'Neill, Hester Gertruida; Sewell, Brian Trevor; Sturrock, Edward; Watermeyer, Jean (Portland Press, 2010)
Determination of the whole-genome consensus sequence of the prototype DS-1 rotavirus using sequence-independent genome amplification and 454® pyrosequencing

Jere, Khuzwayo; Mlera, Luwanika; Van Dijk, Alberdina Aike; O'Neill, Hester Gertruida (Elsevier, 2011)

The prototype DS-1 rotavirus strain, is characterised by a short electropherotype and G2P[4] serotype specificity. Following sequence-independent genome amplification and 454® pyrosequencing of genomic cDNA, differences ...
Sequence-based prediction for vaccine strain selection and identification of antigenic variability in foot-and-mouth disease virus

Blignaut, Belinda; De Beer, Tjaart; Esterhuysen, Jan; Fry, Elizabeth; Haydon, Daniel; Maree, Francois; Matthews, Louise; O'Neill, Hester Gertruida; Opperman, Pamela; Reeve, Richard; Rieder, Elizabeth; Theron, Jacques; Vosloo, Wilna (Public Library of Science, 2010)
Whole genome analyses of African G2, G8, G9, and G12 rotavirus strains using sequence-independent amplification and 454® pyrosequencing

Mlera, Luwanika; Van Dijk, Alberdina Aike; Jere, Khuzwayo C.; Page, Nicola A.; O'Neill, Hester Gertruida (Wiley-Blackwell, 2011)

High mortality rates caused by rotaviruses are associated with several strains such as G2, G8, G9, and G12 rotaviruses. Rotaviruses with G9 and G12 genotypes emerged worldwide in the past two decades. G2 and G8 rotaviruses ...
Whole genome analysis of multiple rotavirus strains from a single stool specimen using sequence-independent amplification and 454® pyrosequencing reveals evidence of intergenotype genome segment recombination

Jere, Khuzwayo; Mlera, Luwanika; Van Dijk, Alberdina Aike; Page, Nicola A.; O'Neill, Hester Gertruida (Elsevier, 2011)

Infection of a single host cell with two or more different rotavirus strains creates conditions favourable for evolutionary mechanisms like reassortment and recombination that can generate novel strains. Despite numerous ...