Browsing Research Output by Author "Prins, Louis Hendrik Albertus"

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Crystal structure of a rearranged cage compound 3-hydroxy-4-aza-8-oxoheptacyclo [9.4.1.0-2,10-, 0 -3,14-, 0-4,9-, 0-9,13-, 0-12,12]tetradecane

Oliver, Douglas W; Van Dyk, Sandra; Malan, Sarel F; Prins, Louis Hendrik Albertus; De Vries, Armand; Caira, Mino R (2008)
Inhibition of monoamine oxidase by indole and benzofuran derivatives

Malan, Sarel Francois; Petzer, Jacobus Petrus; Prins, Louis Hendrik Albertus (Elsevier, 2010)
Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs

Du Preez, Jan; Prins, Louis Hendrik Albertus; Van Dyk, Sandra; Malan, Sarel (Elsevier, 2009)

The blood-brain barrier is formed by the brain capillary endothelium and plays the predominant role in controlling the passage of substances between the blood and the brain. Recent studies on polycyclic structures, i.e. ...
Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxice synthase inhibitors

Petzer, Jacobus; Prins, Louis Hendrik Albertus; Malan, Sarel (2009)

Monoamine oxidase B (MAO-B) and nitric oxide synthase (NOS) have both been implicated in the pathology of neurodegenerative diseases. In an attempt to design dual-target-directed drugs that inhibit both these enzymes, a ...