Now showing items 1-2 of 2

    • Mitochondrial DNA replication and OXPHOS gene transcription show varied responsiveness to Rieske protein knockdown in 143B cells 

      Van Plessis, Lissinda Hester; Levanets, Oskana; Louw, Roan; Pretorius, Petrus Jacobus; Reinecke, Fimmie; Nijtmans, Leo; Smeitink, Jan A.M.; Van der Westhuizen, Francois Hendrikus (Editions Scientifique/Medical Elsevier, 2011)
      Genetic, biochemical and phenotypic diversity is a hallmark of OXPHOS deficiencies. Among the responses frequently reported for these deficiencies is differential expression of several genes involved in mitochondrial ...
    • OXPHOS gene expression and control in mitochondrial disorders 

      Reinecke, Fimmie; Van der Westhuizen, Francois H.; Smeitink, Jan A.M. (2009)
      The cellular consequences of deficiencies of the mitochondrial OXPHOS system include a variety of direct and secondary changes in metabolite homeostasis, such as ROS, Ca2+, ADP/ATP, and NAD/NADH. The adaptive responses to ...