Browsing Research Output by Subject "Reverse genetics"
Now showing items 1-5 of 5
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Establishment of different plasmid only-based reverse genetics systems for the recovery of African horse sickness virus
(Elsevier, 2016)In an effort to simplify and expand the utility of African horse sickness virus (AHSV) reverse genetics, different plasmid-based reverse genetics systems were developed. Plasmids containing cDNAs corresponding to each of ... -
Experimental infection of small ruminants with bluetongue virus expressing Toggenburg Orbivirus proteins
(Elsevier, 2016)Bluetongue virus (BTV) is the prototype orbivirus (Reoviridae family, genus Orbivirus) consisting of more than 24 recognized serotypes or neutralization groups. Recently, new BTV serotypes in goats have been found; serotype ... -
Recombinant rotaviruses rescued by reverse genetics reveal the role of NSP5 hyperphosphorylation in the assembly of viral factories
(ASM, 2020)Rotavirus (RV) replicates in round-shaped cytoplasmic viral factories, although how they assemble remains unknown. During RV infection, NSP5 undergoes hyperphosphorylation, which is primed by the phosphorylation of a single ... -
Replication-deficient particles: new insights into the next generation of bluetongue virus vaccines
(American Society for Microbiology, 2017)Bluetongue virus (BTV) is endemic in many parts of the world, often causing severe hemorrhagic disease in livestock. To date, at least 27 different sero- types have been recognized. Vaccination against all serotypes is ... -
Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)
(BioMed Central, 2016)Background Bluetongue virus (BTV) and African horse sickness virus (AHSV) are distinct arthropod borne virus species in the genus Orbivirus (Reoviridae family), causing the notifiable diseases Bluetongue and African horse ...