Now showing items 1-2 of 2

    • Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B 

      Van der Walt, Mietha M.; Terre'Blanche, Gisella; Petzer, Anél; Petzer, Jacobus P. (Elsevier, 2012)
      Monoamine oxidase (MAO) plays an essential role in the catabolism of neurotransmitter amines. The two isoforms of this enzyme, MAO-A and -B, are considered to be drug targets for the therapy of depression and neurodegenerative ...
    • Selected furanochalcones as inhibitors of monoamine oxidase 

      Robinson, Sarel J.; Petzer, Jacobus P.; Petzer, Anél; Bergh, Jacobus J.; Lourens, Anna C.U. (Elsevier, 2013)
      The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase has previously been illustrated. In a systematic attempt to investigate the effect of heterocyclic substitution on the monoamine ...