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The contribution of the C-824T tyrosine hydroxylase polymorphism to the prevalence of hypertension in a South African cohort: the SABPA study
(Taylor & Francis, 2013)
The C-824T single nucleotide polymorphism in the promoter region of the tyrosine hydroxylase gene has been associated with hypertension. It is well documented that African South Africans exhibit a higher prevalence of ...
Three-year changes of prothrombotic factors in Africans with a high clinical suspicion of obstructive sleep apnea
(Schattauer Publishers, 2016)
A hypercoagulable state might be one important mechanism linking obstructive sleep apnea (OSA) with incident myocardial infarction and stroke. However, previous studies on prothrombotic factors in OSA are not uniform and ...
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: the SABPA study
(Elsevier, 2017)
"Background: Oestradiol has a protective effect on coronary artery health in women but the effect it has on men, is controversial. A translational approach was followed to assess whether sex hormone levels are associated ...
Emotional stress as a risk for hypertension in sub-Saharan Africans: Are we ignoring the odds?
(Springer Link, 2017)
"Globally most interventions focus on improving lifestyle habits and treatment regimens to combat hypertension as a non-communicable disease (NCD). However, despite these interventions and improved medical treatments, blood ...
A challenged sympathetic system is associated with retinal vascular calibre in a black male cohort: the SABPA Study
(Intech, 2016)
Sympathetic system hyperactivity and depression are related to cardiac remodelling in Black men. We investigated whether sympathetic system hyperactivity and depressive symptoms are related to retinal vascular dysregulation. ...
Coping facilitated troponin T increases and hypo-responsivity in the copeptin-HPA-axis during acute mental stress in a black cohort: the SABPA study
(Elsevier, 2019)
Background
Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an ...
Blunted neuro-endocrine responses linking depressive symptoms and ECG left ventricular hypertrophy in black Africans: the SABPA study
(Wolters Kluwer, 2014)
Objective: Chronic psychosocial stress as experienced in an urban environment plays an important role in the aetiology of depression-related cardiovascular risk. It is uncertain whether acute mental stress responses aggravate ...
Coping mechanisms, perception of health and cardiovascular dysfunction in Africans
(Elsevier, 2006)
The purpose of this study was to compare active and passive coping strategies of Africans with perception of own health and cardiovascular data. The subjects included 236 apparently healthy Africans (men = 109; women = 127). ...
Specific coping strategies of Africans during urbanization: comparing cardiovascular responses and perception of health data
(Elsevier, 2006)
Specific coping mechanisms of Africans during urbanization were compared to and correlated with cardiovascular responses and perception of health data. Subjects included men (N = 286) and women (N = 360). The COPE questionnaire ...
Coping disability of Africans during urbanization: a risk marker in the development of lifestyle diseases?
(Nova Science Publishers, 2008)
Urbanization with accompanying insecurities and disruption in African social relationships is consistent with an increase in the prevalence of lifestyle diseases such as hypertension and the metabolic syndrome. The individual ...