Browsing Faculty of Health Sciences by Author "569408c0-f0d8-4401-bea7-bc7857866011"
Now showing items 1-9 of 9
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The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
Schutte, Aletta E.; Uys, Aletta S.; Burger, Adele; Mels, Catharina M.C.; Kruger, Ruan; Smith, Wayne; Fourie, Carla M.T.; Botha, Shani; Lammertyn, Leandi; Van Rooyen, Johannes M.; Gafane-Matemane, Lebo F.; Mokwatsi, Gontse G.; Breet, Yolandi; Kruger, H. Salome; Van Zyl, Tertia; Pieters, Marlien; Zandberg, Lizelle; Louw, Roan; Moss, Sarah J.; Huisman, Hugo W. (Sage, 2019)Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ... -
BDNF increases associated with constant troponin T levels and may protect against poor cognitive interference control: the SABPA prospective study
Jansen van Vuren, Esmé; Malan, Leoné; Von Känel, Roland; Lammertyn, Leandi; Malan, Nicolaas T. (Wiley, 2019)Background: Brain‐derived neurotrophic factor (BDNF) modulates brain health and cognition, which can interfere with executive cognitive function. BDNF was impli-cated with microcirculatory ischaemia and may reflect ... -
D-dimer relates positively with increased blood pressure in black South Africans: the SABPA study
Lammertyn, Leandi; Schutte, Aletta E.; Pieters, Marlien; Schutte, Rudolph (Elsevier, 2014)Introduction Hypertension is highly prevalent in black South Africans in which morbidity and mortality from stroke are on the increase. Elevated blood pressure and haemostatic markers can induce changes in blood rheology ... -
Leptin and its relation to autonomic activity, endothelial cell activation and blood pressure in a young black and white population: the African-PREDICT study
Ahiante, Blessing O.; Smith, Wayne; Lammertyn, Leandi; Schutte, Aletta E. (Thieme, 2018)An increasing prevalence of obesity-related hypertension is observed in the youth and may have severe consequences for future cardiovascular disease development. Previous studies portrayed leptin as a potential factor ... -
Leptin and the vasculature in young adults: the African‐PREDICT study
Ahiante, Blessing O.; Smith, Wayne; Lammertyn, Leandi; Schutte, Aletta E. (Wiley, 2019)Background and aim Information regarding the effect of leptin on the vasculature in young healthy adults at risk for cardiovascular disease development is limited. We therefore examined the associations between measures ... -
Masked hypertension and its associated cardiovascular risk in young individuals: the African-PREDICT study
Thompson, Jane E.S.; Smith, Wayne; Ware, Lisa J.; Mels, Catharina M.C.; Van Rooyen, Johannes M.; Huisman, Hugo W.; Malan, Leoné; Malan, Nicolaas T.; Lammertyn, Leandi; Schutte, Aletta E. (Springer Nature, 2016)Hypertension prevalence is increasing globally, yet little is known about the occurrence of masked hypertension (MHT) in young, sub-Saharan African adults, and how it relates to elevated cardiovascular risk. The African-PREDICT ... -
Prospective associations between cardiac stress, glucose dysregulation and executive cognitive function in Black men: the Sympathetic activity and ambulatory blood pressure in Africans study
Jansen van Vuren, Esmé; Malan, Leoné; Von Känel, Roland; Lammertyn, Leandi; Malan, Nicolaas T. (Sage, 2018)Objective: Glucose dysregulation is an independent risk factor for cardiovascular and neurodegenerative disease development through synaptic dysfunction resulting in cognitive decline. The aim of this study was to study ... -
Quantification of systemic renin-angiotensin system peptides of hypertensive black and white African men established from the RAS-Fingerprint
Van Rooyen, J.M.; Huisman, H.W.; Mels, C.M.C.; Kruger, R.; Malan, L.; Botha, S.; Lammertyn, L.; Gafane, L.; Schutte, A.E. (Sage, 2016)Objective: The objective of this study was to make use of a quantitative and qualitative approach comparing the systemic renin-angiotensin system (RAS) of hypertensive black and white African men by using RAS equilibrium ... -
Retinal vessel caliber and vessel reaction to light flicker in true normotensive young healthy black and white adults: the African-PREDICT study
Smith, Wayne; Lammertyn, Leandi; Huisman, Hugo; Schutte, Aletta; Korliar, Konstantin (Karger, 2019)A detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides insight into the pathogenesis of systemic vascular ...