Browsing Faculty of Health Sciences by Title
Now showing items 134-153 of 2383
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Appraisal of ozone as biologically active molecule and experimental tool in biomedical sciences
(Springer, 2011)Ozone (O3) (CAS 10028-15-6) is a major air industrial pollutant and is well known for its very strong oxidative actions which affords the molecule its useful antimicrobial and deodorizing properties, but also its potential ... -
Appropriate and non-medical use of methylphenidate by residence students at a South African tertiary institution
(LAM Publications, 2017)The purpose was to determine to what degree residence students from a tertiary academic institution use methylphenidate in both non-medical and appropr iate manners in the South African ... -
Approximation-based integral versus differential isoconversional approaches to the evaluation of kinetic parameters from thermogravimetry: kinetic analysis of the dehydration of a pharmaceutical hydrate
(Springer, 2016)The relative accuracies of approximation-based integral versus differential isoconversional approaches for ‘actual’ E determination were investigated on experimental dehydration data of roxithromycin monohydrate ... -
Are antiretroviral prescribed according to the recommended prescribed daily doses in the private healthcare sector in South Africa
(AOSIS, 2011)Current antiretroviral treatment (ART) guidelines recommend different combinations that have led to major improvements in the management of HIV and AIDS in the developed and developing world. With the rapid approval of ... -
Are behavioural risk factors to be blamed for the conversion from optimal blood pressure to hypertensive status in black South Africans? A 5-year prospective study
(Oxford University Press, 2012)Background Longitudinal cohort studies in sub-Saharan Africa are urgently needed to understand cardiovascular disease development. We, therefore, explored health behaviours and conventional risk factors of African individuals ... -
Are community pharmacists and nutritionists capable for obesity management in Pakistan? A cross-sectional study
(Marmara University, Faculty of Pharmacy, 2016)The main objective of the study was to evaluate knowledge and perceptions among community pharmacists and nutritionists/ dietitians regarding obesity management in Pakistan. A semi-structured questionnaire was distributed ... -
Are the American Heart Association/American College of Cardiology high blood pressure guidelines fit for global purpose? Thoughts from the International Society of Hypertension
(American Heart Association, 2018)In 2017, the American College of Cardiology (ACC), the American Heart Association (AHA), and 9 other American societies released guidelines for the prevention, detection, evaluation, and management of high blood pressure ... -
Are there sufficient number of exercise therapists in South Africa in order to equitably manage the noncommunicable disease epidemic?
(Sage, 2019)The mortality of South African noncommunicable diseases (NCDs) is rising. One of its primary contributors is physical inactivity. Therefore, South African National Health Plan included exercise therapy as part of their ... -
Artemisia afra, a controversial herbal remedy or a treasure trove of new drugs?
(Elsevier, 2019)Ethnoparmacological relevance Artemisia afra is one of the most widely used herbal remedies in South Africa. This highly aromatic shrub is used to treat various disorders including coughs, colds, influenza, and malaria. ... -
The artemisinin derivative artemisone is a potent inhibitor of human cytomegalovirus replication
(American Society for Microbiology, 2018)Human cytomegalovirus (HCMV) is a major cause of disease in immunocompromised individuals and the most common cause of congenital infection and neurosensorial disease. The expanding target populations for HCMV antiviral ... -
Artemisinin quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity
(Elsevier, 2010)Novel artemisinin–quinoline hybrid-dimers were synthesized from dihydroartemisinin and different aminoquinolines at elevated temperatures (90–110 °C). All compounds were obtained as the β-isomers and were tested against ... -
Artemisone and artemiside are potent panreactive antimalarial agents that also synergize redox imbalance in Plasmodium falciparum transmissible gametocyte stages
(American Society for Microbiology, 2018)The emergence of resistance toward artemisinin combination therapies (ACTs) by the malaria parasite Plasmodium falciparum has the potential to severely compromise malaria control. Therefore, the development of new artemisinins ... -
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus
(Elsevier, 2019)We have recently shown that the artemisinin derivative artemisone, which was screened against malaria in human clinical studies, is a potent inhibitor of human cytomegalovirus (HCMV). Here we evaluated the antiviral effect ... -
Artemisone inhibits in vitro and in vivo propagation of Babesia bovis and B. bigemina parasites
(Elsevier, 2013)Artemisone was evaluated, in in vitro and in vivo, for control of bovine babesiosis caused by Babesia bigemina and Babesia bovis parasites. In vitro, artemisone reduced parasitemia in a dose-dependent manner: the inhibitory ... -
Arterial stiffness profiles: investigating various sections of the arterial tree of African and caucasian people
(Informa healthcare, 2011)In Africans, arterial stiffness progression seems more pronounced compared to Caucasians. We compared the arterial stiffness profiles of different age groups and focused on muscular arteries and two more central arterial ... -
Arterial stiffness, ambulatory blood pressure and low-grade albuminuria in non-diabetic African and caucasian men: the SABPA study
(Nature Publishing Group, 2011)Recent evidence suggests that low-grade urinary albumin excretion is a marker of early general attenuation of vascular function, but studies are limited to Caucasian population groups. We compared low-grade urinary albumin ... -
Artificial membranes in combination with selected natural oils for in vitro drug passive diffusion screening in Ussing type chamber apparatus applied to gastro-retentive systems
(Taylor & Francis, 2020)This study aimed at developing an effective in vitro technique for the screening of drug passive diffusion utilising artificial membranes in combination with three selected oils (i.e. cognac, emu, and olive oil). Artificial ... -
ASSAf consensus study on the ethical, legal and social implications of genetics and genomics in South Africa
(ASSAf, 2018)South Africa is home to one of the most genetically diverse populations in the world, which, combined with its high disease burden and high-quality infrastructure, makes our country a prime location for conducting genetics ... -
Assessing a portable, real‐time display handheld meter with UV‐A and UV‐B sensors for potential application in personal sun exposure studies
(Wiley, 2018)Background Observing accurate real‐time measurements of solar ultraviolet radiation (UVR) levels is important since personal excess sun exposure is associated with skin cancers. Handheld measurement devices may be helpful ...