Browsing Faculty of Health Sciences by Title
Now showing items 140-159 of 2386
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Are community pharmacists and nutritionists capable for obesity management in Pakistan? A cross-sectional study
(Marmara University, Faculty of Pharmacy, 2016)The main objective of the study was to evaluate knowledge and perceptions among community pharmacists and nutritionists/ dietitians regarding obesity management in Pakistan. A semi-structured questionnaire was distributed ... -
Are the American Heart Association/American College of Cardiology high blood pressure guidelines fit for global purpose? Thoughts from the International Society of Hypertension
(American Heart Association, 2018)In 2017, the American College of Cardiology (ACC), the American Heart Association (AHA), and 9 other American societies released guidelines for the prevention, detection, evaluation, and management of high blood pressure ... -
Are there sufficient number of exercise therapists in South Africa in order to equitably manage the noncommunicable disease epidemic?
(Sage, 2019)The mortality of South African noncommunicable diseases (NCDs) is rising. One of its primary contributors is physical inactivity. Therefore, South African National Health Plan included exercise therapy as part of their ... -
Artemisia afra, a controversial herbal remedy or a treasure trove of new drugs?
(Elsevier, 2019)Ethnoparmacological relevance Artemisia afra is one of the most widely used herbal remedies in South Africa. This highly aromatic shrub is used to treat various disorders including coughs, colds, influenza, and malaria. ... -
The artemisinin derivative artemisone is a potent inhibitor of human cytomegalovirus replication
(American Society for Microbiology, 2018)Human cytomegalovirus (HCMV) is a major cause of disease in immunocompromised individuals and the most common cause of congenital infection and neurosensorial disease. The expanding target populations for HCMV antiviral ... -
Artemisinin quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity
(Elsevier, 2010)Novel artemisinin–quinoline hybrid-dimers were synthesized from dihydroartemisinin and different aminoquinolines at elevated temperatures (90–110 °C). All compounds were obtained as the β-isomers and were tested against ... -
Artemisone and artemiside are potent panreactive antimalarial agents that also synergize redox imbalance in Plasmodium falciparum transmissible gametocyte stages
(American Society for Microbiology, 2018)The emergence of resistance toward artemisinin combination therapies (ACTs) by the malaria parasite Plasmodium falciparum has the potential to severely compromise malaria control. Therefore, the development of new artemisinins ... -
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus
(Elsevier, 2019)We have recently shown that the artemisinin derivative artemisone, which was screened against malaria in human clinical studies, is a potent inhibitor of human cytomegalovirus (HCMV). Here we evaluated the antiviral effect ... -
Artemisone inhibits in vitro and in vivo propagation of Babesia bovis and B. bigemina parasites
(Elsevier, 2013)Artemisone was evaluated, in in vitro and in vivo, for control of bovine babesiosis caused by Babesia bigemina and Babesia bovis parasites. In vitro, artemisone reduced parasitemia in a dose-dependent manner: the inhibitory ... -
Arterial stiffness profiles: investigating various sections of the arterial tree of African and caucasian people
(Informa healthcare, 2011)In Africans, arterial stiffness progression seems more pronounced compared to Caucasians. We compared the arterial stiffness profiles of different age groups and focused on muscular arteries and two more central arterial ... -
Arterial stiffness, ambulatory blood pressure and low-grade albuminuria in non-diabetic African and caucasian men: the SABPA study
(Nature Publishing Group, 2011)Recent evidence suggests that low-grade urinary albumin excretion is a marker of early general attenuation of vascular function, but studies are limited to Caucasian population groups. We compared low-grade urinary albumin ... -
Artificial membranes in combination with selected natural oils for in vitro drug passive diffusion screening in Ussing type chamber apparatus applied to gastro-retentive systems
(Taylor & Francis, 2020)This study aimed at developing an effective in vitro technique for the screening of drug passive diffusion utilising artificial membranes in combination with three selected oils (i.e. cognac, emu, and olive oil). Artificial ... -
ASSAf consensus study on the ethical, legal and social implications of genetics and genomics in South Africa
(ASSAf, 2018)South Africa is home to one of the most genetically diverse populations in the world, which, combined with its high disease burden and high-quality infrastructure, makes our country a prime location for conducting genetics ... -
Assessing a portable, real‐time display handheld meter with UV‐A and UV‐B sensors for potential application in personal sun exposure studies
(Wiley, 2018)Background Observing accurate real‐time measurements of solar ultraviolet radiation (UVR) levels is important since personal excess sun exposure is associated with skin cancers. Handheld measurement devices may be helpful ... -
Assessing mental health services in a rural setting: service providers’ perspective
(Taylor & Francis, 2018)Addressing the inadequate and poor provision of mental health services in rural areas is a world-wide challenge. Most people with mental illness in these areas do not have access to mental health services. Using eight ... -
Assessing the construct validity of nutrient profiling models for restricting the marketing of foods to children in South Africa
(Nature, 2020)Background In an effort to combat childhood obesity the WHO has called on governments to restrict the marketing of unhealthy foods to children. Regulators have turned to nutrient profiling (NP) to provide the evidence for ... -
Assessing tobacco use in an African population: serum and urine cotinine cut-offs from South Africa
(Elsevier, 2019)Background Cotinine, a nicotine metabolite, is used to measure tobacco use and exposure, but recommended cut-offs to differentiate tobacco users from those exposed through the environment range from 3 to 58 ng/ml in serum, ... -
Assessment of dermal exposure and skin condition of workers exposed to nickel at a South African base metal refinery
(Oxford Univ Press, 2010)Objectives: The objectives of this study were to assess dermal exposure of cell workers to nickel at a South African base metal refinery and to characterize their skin condition by measuring the skin hydration and trans ... -
Assessment of paper tip angular position, carryover, matrix effects and dried blood spot storage effect on paper spray mass spectrometry
(RSC, 2020)Paper Spray (PS) ionization has been demonstrated extensively for rapid quantitation of pharmaceuticals in dried matrix spots. In this study, experimental and validation parameters of paper spray mass spectrometry were ...