Browsing Faculty of Health Sciences by Title
Now showing items 187-206 of 1614
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Cancer patients' ilness expierences during a group intervention
(PSYSSA, 2008) -
Cancer treatment in South Africa: a narrative literature review
(Taylor & Francis, 2012)Due to the advances in cancer treatment, there are a growing number of cancer survivors. Finishing treatment rarely indicates the end of the cancer experience. As a result, cancer management has shifted from an acute care ... -
A canning quality model for small white bean lines selected for breeding (Phaseolus vulgaris L.)
(Forum Press International, 2008) -
Carbamate substituted 2-amino-4,6-diphenylpyrimidines as adenosine receptor antagonists
(Elsevier, 2016)A novel series of carbamate substituted 2-amino-4,6-diphenylpyrimidines was evaluated as potential dual adenosine A1 and A2A receptor antagonists. The majority of the synthesised compounds exhibited promising dual affinities, ... -
Carbon-14 radiolabeling and in vivo biodistribution of a potential anti-TB compound
(Wiley, 2015)A potential anti-TB compound bearing a nitroimidazole moiety from iThemba Pharmaceuticals TB chemical library exhibits promising in vitro activity in the microplate almar blue assay (MABA) with a minimum inhibitory ... -
Carbon-14 radiolabelling and tissue distribution evaluation of a potential anti-TB compound
(Wiley, 2016)This paper describes a five-step synthesis of a carbon-14-labelled pyrazole compound (11). A total of 2.96 MBq of 11 was obtained with the specific activity of 2242.4 MBq/mmol. The radiochemical purity was >99%, and the ... -
Carbon‐14 radiolabeling and tissue distribution evaluation of MMV390048
(Wiley, 2016)The antimalarial compound MMV390048 ([14C]-11) was labeled with carbon-14 isotope via a 3-step synthesis. It was obtained in a 15.5% radiochemical overall yield from carbon-14 labeled methyl iodide with a radiochemical ... -
Cardiac
(Wiley, 2016)This chapter highlights various non-automated classical in vitro techniques used today to evaluate drug effects on cardiac electrophysiology. It then outlines a three-pronged preclinical initiative called the Comprehensive ... -
Cardiac troponin T as early marker of subclinical cardiovascular deterioration in black hypertensive women
(Elsevier, 2017)Background Hypertensive heart disease is a rising concern, especially among black South African women. As high sensitivity cardiac troponin T (cTnT) is a marker of cardiomyocyte damage, we determined the potential link ... -
Cardiac, respiratory and postural influences on venous return of internal jugular and vertebral veins
(Elsevier, 2017)It is known from physiology that heartbeat and respiration influence venous return, but little is known regarding the extent to which these two factors affect flow. In this study, we estimated the prevalence of cardiac- ... -
Cardiometabolic changes in treated versus never treated HIV-infected Black South Africans: the PURE study
(Elsevier, 2014)Background The use of antiretroviral treatment is known to be accompanied by several negative health outcomes and may negatively affect a country such as South Africa, which is the most burdened by the human immunodeficiency ... -
Cardiometabolic markers to identify cardiovascular disease risk in HIV-infected black South Africans
(2014)Background. The prevalence of HIV is the highest in sub-Saharan Africa; South Africa (SA) is one of the most affected countries with the highest number of adults living with HIV infection in the world. Besides ... -
Cardiovascular disease and nutrition: the use of food-based dietary guidelines for prevention in Africa
(South African Heart Association, 2011)There is no doubt that morbidity and mortality from cardiovascular disease (CVD) are increasing in many African countries. Research and implementation of public health nutrition programmes in the developed world have shown ... -
Cardiovascular function and psychological distress in urbanised black South African : The SABPA study
(Clinics cardiv publishing, 2010) -
Cardiovascular function is not associated with creatine kinase activity in a black African population: the SABPA study
(Biomed Central Ltd, 2016)Background: Higher creatine kinase (CK) activity is associated with the development of cardiovascular disease in black African populations. We compared CK activity and investigated associations of blood pressure with CK ... -
Cardiovascular health screening among South African students
(Sabinet, 2012)Stress is an unavoidable part of everyday life due to the demands and stressors associated with modern lifestyle. Health risks provoked by this increasingly prevalent condition lead to cardiovascular disease, which ultimately ... -
Cardiovascular risk and events in 17 low-, middle-, and high-income countries
(Massachusetts Medical Society, 2014)BACKGROUND More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons are unknown. ... -
Cardiovascular risk stratification and blood pressure variability on ambulatory and home blood pressure measurement
(Current Medicine Group, 2014)Abstract Variability is a phenomenon attributed to most biological processes and is a particular feature of blood pressure (BP) that concerns many physicians regarding the clinical meaning and the impact on their clinical ... -
Cardiovascular safety pharmacology studies in dogs enabled for a poorly soluble molecule using spray-dried dispersion: impact on lead selection
(Elsevier, 2016)The aim of this study was to identify an adequate formulation for a poorly soluble lead molecule (BI-A) that would achieve sufficiently high plasma concentrations after oral administration in dogs to enable a robust ... -
Cardiovascular, cortisol and coping responses in urbanised Africans: The SAPBA Study
(Clinics Cardive Publishers, 2012)Objectives: To assess the relationships between progression of target-organ damage and cardiovascular, cortisol and coping responses in black urban Africans. Methods: Urban black African gender groups (n = 200) aged 21-62 ...
