Browsing Faculty of Health Sciences by Title
Now showing items 250-269 of 2386
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Bio-behavioural studies into the antidepressant and antipsychotic-like effects of Garcinia mangostana Linn extract and alpha-mangostin as adjunctive-or mono-therapy in a rodent model of schizophrenia
(Wiley, 2019)Introduction: Garcinia mangostana Linn (GML) or mangosteen has anti-inflammatory, antioxidant and neuroprotective actions. Its bioactive constituents, α- , β- , and γ- mangostin also inhibit cAMP ... -
Bioaccumulation and subchronic toxicity of 14 nm gold nanoparticles in rats
(MDPI, 2016)Colloidal suspensions of 14 nm gold nanoparticles (AuNPs) were repeatedly administered intravenously at three dose levels (0.9, 9 and 90 µg) to male Sprague Dawley rats weekly for 7 weeks, followed by a 14-day washout ... -
Bioactive albumin-based carriers for tumour chemotherapy
(Bentham Science, 2014)Proteins are posed as the natural counterpart of the synthetic polymers for the development of drug delivery systems and few of them, have been regarded safe for drug delivery purposes by the United States Food and Drug ... -
Bioavailable IGF-1 and its relation to the metabolic syndrome in a bi-ethnic population of men and women
(Georg Thieme Verlag, 2016)Insulin-like growth factor 1 (IGF-1), an insulin sensitivity and vasculoprotective factor, associates negatively with the metabolic syndrome. However, IGF-1 is reduced by factors such as inflammation, oxidative stress and ... -
Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: the African-PREDICT study
(Elsevier, 2018)Low circulating levels of insulin-like growth factor-1 (IGF-1) are associated with endothelial dysfunction, subsequently leading to the development of cardiovascular disease. Objective To better understand the early ... -
Biodistribution (as determined by the radiolabelled equivalent) of a gold(III) bis(pyrrolide-imine) Schiff base complex: a potential chemotherapeutic
(Wiley, 2013)The biodistribution of an N2N2 0 tetradentate gold(III) chelate, which is known to be cytotoxic towards a range of human cancer cell lines, was determined by a radiolabelled equivalent of the compound. The 198Au-labelled ... -
Biodistribution and dosimetry of 195mPt-cisplatin in normal volunteers
(Schattauer, 2013)195mPt-cisplatin is regarded as a promising imaging agent for optimizing dosage in patients receiving cisplatin chemotherapy. We investigated the whole-body distribution and radiation dosimetry of 195mPt-cisplatin in ... -
Biodistribution and pharmacokinetics of I-131 labelled 4- Iodophenylacetic acid
(Bentham Science, 2012)Abstract: Phenylacetate has been reported to have a potent anti-proliferative and anti-differentiating effect in haematological malignancies and in solid tumours at non-toxic concentrations. This study is a preliminary ... -
Biodistribution of a potential chemotherapeutic, dinuclearbisphosphinogold(I) dithiocarbamate, as determined by its 198Au radiolabelled analogue
(Springer, 2015)Dinuclearbisphosphinogold(I) dithiocarbamato, BPDTC, was previously found to have antitumour activity in vitro. 198Au radiolabelled BPDTC (radiochemical yield of 70 ± 6 % and radiochemical purity of[95 %) was used to ... -
The biology of homosexuality and its implications for human rights in South Africa.
(LexisNexus, 2009) -
Biomarkers of nutrition for development—iodine review1-4
(American Society for Nutrition, 2014)The objective of the Biomarkers of Nutrition for Development (BOND) project is to provide state-of-the-art information and service with regard to selection, use, and interpretation of biomarkers of nutrient exposure, status, ... -
Biomechanical benefits of symmetrical strengthening of hip extensors among athletes: a review
(LAM Publications Limited, 2016)There is abundant literature encouraging athletes to engage in concurrent strength training. However, little emphasis is placed on the value of biomechanics with regard to symmetrical strengthening of force-couple ... -
Biometrology guidelines for the in vivo assessment of skin surface pH in nonclinical settings
(Springer, 2017)Skin surface pH plays an important role in the maintenance of skin barrier integrity and epidermal homeostasis. In workplace environments, myriad exposures may alter the skin surface pH and influence development of skin ... -
Biometrology guidelines for the in vivo assessment of transepidermal water loss and skin hydration in nonclinical settings
(Springer, 2017)It is becoming evident that assessment of skin exposure to physical and chemical stressors in workplaces should be accompanied by the assessment of skin barrier function at the time of exposure. “Real-life” occupational ... -
Black adults’ perceptions of healthy family functioning
(Taylor & Francis, 2012)This study explores Black adults’ perceptions of factors that contribute to healthy family functioning. Qualitative interviews were conducted with 18 Black participants between the ages of 26 and 54. They responded to a ... -
Black South African farm workers beliefs about HIV
(ELSEVIER, 2013)Black South African farm workers' context of an isolated lifestyle and lack of education and resources might lead to unique beliefs that influence their understanding and behavior regarding HIV infection. An exploration ... -
Blood glucose and nocturnal blood pressure in African and caucasian men: the SABPA study
(Elsevier, 2011)To investigate the relationship between nocturnal blood pressure and chronically elevated blood glucose to determine if these elevated blood glucose concentrations contribute to a non-dipping blood pressure, especially in ... -
Blood glutathione and subclinical atherosclerosis in African men: the SABPA study
(Oxford Univ Press, 2009)Background: Sub-Saharan Africans face an increasing burden of hypertension and related cardiac and cerebrovascular morbidity and mortality, making the identification of factors leading to early vascular abnormalities ... -
Blood pressure variability in risk stratification: What does it add?
(Wiley, 2014)1. In this minireview we address the predictive value of blood pressure variability, over and beyond level of pressure, in randomly selected population samples. All reviewed studies had sufficient power, long follow-up ... -
Blood pressure variability is significantly associated with ECG left ventricular mass in normotensive Africans: the SABPA study
(Nature Publishing Group, 2011)The prognostic significance of blood pressure (BP) variability has lately enjoyed considerable attention. The need for early markers of cardiovascular dysfunction is imperative in black South Africans who have a significant ...