Browsing Faculty of Health Sciences by Title
Now showing items 279-298 of 2377
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Boys in middle childhood placed in a clinic school: experiences of sexual abuse.
(South African Society on the Abuse of Children (SAPSAC), 2014)This study formed part of a larger research project, which aimed to develop an intervention strategy to support sexually abused boys in their middle childhood placed in a clinic school. The experiences of these boys were ... -
Brain-derived neurotrophic factor: the neurotrophin hypothesis of psychopathology
(Cambridge Univ Press, 2008)While monoaminergic hypotheses of psychopathology remain popular, there has been growing interest in the role of neurotrophins in neuropsychiatric disorders. Basic laboratory work has documented the importance of neurotrophins ... -
Brain-derived-neurotrophic-factor, dynamic retinal vessel responses during flicker light and stroke risk: the SABPA study
(Karger, 2019)Assessment of the retinal vessels’ structure and function provides an automated and objective approach to noninvasively assess the condition of the cerebral microvasculature and indicates susceptibility for stroke. ... -
Breaching the skin barrier through temperature modulations
(Elsevier, 2015)The impermeability of the stratum corneum often hinders the transport of molecules across the skin. Temperature modulations in the skin and the application of local heat both have the potential of circumventing this problem ... -
Breast milk and erythrocyte fatty acid composition of lactating women residing in a peri‑urban South African township
(Elsevier, 2020)Data on breast milk fatty acid (FA) composition in South African lactating women in relation to their FA status, as well as on potential compositional changes within feed, are limited. The aim of this study was to assess ... -
Breast-milk iodine concentrations, iodine status, and thyroid function of breastfed infants aged 2-4 months and their mothers residing in a South African township
(Galenos Yayincilik, 2016)Objective: Lactating women and their infants are susceptible to iodine deficiency and iodine excess. In South Africa, no data exist on the iodine status and thyroid function of these vulnerable groups. Methods: In a ... -
Breastfeeding during the COVID-19 pandemic: a literature review for clinical practice
(BMC, 2020)Background The COVID-19 pandemic is disrupting normal life globally, every area of life is touched. The pandemic demands quick action and as new information emerges, reliable synthesises and guidelines for care are urgently ... -
The BRICS Council for Exercise and Sport Science (BRICSCESS) - a new era has dawned
(Elsevier, 2018)BRICS is the acronym for an international association of 5 major emerging national economies: Brazil, Russia, India, China, and South Africa. The BRICS Council of Exercise and Sports Science was founded to address the ... -
BRICS to BRICSCESS: a perspective for practical action in the promotion of healthy lifestyles to improve public health in five countries
(Elsevier, 2019)A brief historical summary of BRICS countries and the BRICS Council of Exercise and Sport Science (BRICSCESS) is presented. BRICSCESS functions to facilitate the accomplishment of the various tasks such as to establish ... -
Brief report on a resilience workshop for professional rugby players
(Faculty of Education. University of Alicante, 2019)This brief report constitutes an evidence based, evaluation of a resilience workshop for 328 male professional rugby players, with mean age of 25 and standard deviation (SD) of 4.7 years. Quantitative findings revealed ... -
C2-substituted quinazolinone derivatives exhibit A1 and/or A2A adenosine receptor affinities in the low micromolar range
(Elsevier, 2020)Antagonists of the adenosine receptors (A1 and A2A subtypes) are widely researched as potential drug candidates for their role in Parkinson’s disease-related cognitive deficits (A1 subtype), motor dysfunction (A2A subtype) ... -
C3 amino-substituted chalcone derivative with selective adenosine rA1 receptor affinity in the micromolar range
(Springer, 2020)To identify novel adenosine receptor (AR) ligands based on the chalcone scaffold, herein the synthesis, characterization and in vitro and in silico evaluation of 33 chalcones (15–36 and 37–41) and structurally related ... -
C6- and C7-substituted 3,4-dihydro-2(1H)-quinolinones as inhibitors of monoamine oxidase
(Thieme, 2017)Purpose Monoamine oxidase (MAO) inhibitors are considered to be useful therapeutic agents and isoform specific inhibitors are employed for the treatment of depression and Parkinson’s disease. MAO inhibitors are also under ... -
C679X loss-of-function PCSK9 variant lowers fasting glucose levels in a black South African population: a longitudinal study
(Elsevier, 2018)Aims To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin. Methods We conducted ... -
Caffeine as a lead compound for the design of therapeutic agents for the treatment of Parkinson’s disease
(Bentham Science, 2015)The current pharmacological therapies for the treatment of Parkinson’s disease are mostly inadequate and recent, improved therapeutic agents are required. Two important molecular targets for the design of anti-parkinsonian ... -
Caffeine improves triathlon performance: a field study in males and females
(Human Kinetics, 2018)The ergogenic effect of caffeine on endurance exercise is commonly accepted. We aimed to elucidate realistically the effect of caffeine on triathlon event performance using a field study design, while allowing investigation ... -
A call for improved reporting on serious adverse events in clinical trials
(Wolters Kluwer, 2019)Following SPRINT (Systolic Blood Pressure Intervention Trial) [1], several investigations including systematic reviews and meta-analyses confirmed that reducing SBP to levels below 140 mmHg markedly reduces the risk of ... -
Can ambulatory blood pressure measurements substitute assessment of subclinical cardiovascular damage?
(Kluwer, 2012)Objective: We have previously demonstrated that markers of subclinical organ damage (SOD) improve cardiovascular risk prediction in healthy individuals. We wanted to investigate whether this additive effect of SOD was due ... -
Can South African biokineticists function as recreational therapists: a review of the minimum training standards relevant to each profession?
(Taylor & Francis, 2020)In South Africa, the profession of Recreational Therapy is recognized by neither the Health Professions Council South Africa (HPCSA) nor the Allied Health Professions Council of South Africa (AHPCSA). However, the South ... -
Can South African biokineticists function as recreational therapists: a review of the minimum training standards relevant to each profession?
(Taylor & Francis, 2020)In South Africa, the profession of Recreational Therapy is recognized by neither the Health Professions Council South Africa (HPCSA) nor the Allied Health Professions Council of South Africa (AHPCSA). However, the South ...