Browsing Faculty of Health Sciences by Title
Now showing items 79-98 of 2385
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Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study
(Elsevier, 2015)Background: Alcohol consumption is proposed to be the third most important modifi able risk factor for death and disability. However, alcohol consumption has been associated with both benefi ts and harms, and previous ... -
Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study
(BMJ Publishing Group, 2018)Objective To investigate the association between alcohol consumption (at baseline and over lifetime) and non-fatal and fatal coronary heart disease (CHD) and stroke. Design Multicentre case-cohort study. Setting A study ... -
Alcohol intake, hypertension development and mortality in black South Africans
(Sage Publishing, 2016)Background: Excessive alcohol intake is a risk factor for cardiovascular disease (CVD) and predicts cardiovascular and all-cause mortality. We determined which alcohol marker (self-reported alcohol intake, gamma-glutamy ... -
Alcohol metabolism and health hazards associated with alcohol abuse in a South African context: a review
(Medpharm Publications, 2010)The World Health Organization recently stated that alcohol consumption is the fifth leading cause of death worldwide and that intakes are increasing, especially in developing countries. Alcohol-related effects are major ... -
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
(Elsevier, 2018)Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. ... -
Alcohol use and misuse among school-going adolescents in Thailand: results of a national survey in 2015
(MDPI, 2019)The aim of this study was to assess the prevalence of alcohol use and misuse, and to identify its associated factors among in-school adolescents in the 2015 Thailand Global School-based Student Health Survey (GSHS). The ... -
Aldosterone and renin in relation to surrogate measures of sympathetic activity: the SABPA study
(Clinics Cardive Publishing, 2019)Introduction: Hypertension, particularly in black populations, is often accompanied by augmented sympathetic nervous system activity and suppressed renin activity, indicative of possible blood pressure (BP) dysregulation. ... -
Alkaline phosphatase and arterial structure and function in hypertensive African men: the SABPA study
(Elsevier, 2013)Background: Vascular calcification is believed to be due to the conversion of vascular smooth muscle cells into osteoblast-like cells and is associated with mortality. Since hypertension and related mortality in Africans ... -
All headaches are not equal: a review of migraine as a state of brain dysfunction
(Taylor & Francis, 2018)Individuals suffering from migraine headache, or migraineurs as they are often referred to, and the clinicians treating them are well-informed of the excruciating and debilitating nature of such episodes. However, the ... -
Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression
(Springer Nature, 2013)Neuropeptide Y (NPY) has been implicated in depression, emotional processing and stress response. Part of this evidence originates from human single-nucleotide polymorphism (SNP) studies. In the present study, we report ... -
Aloe vera gel and whole leaf extract: functional and versatile excipients for drug delivery?
(Taylor & Francis, 2019)Aloe vera (L.) Burm.f. (Aloe barbadensis Miller) is a perennial xerophyte plant that has many medicinal applications. A. vera leaves contain water storage tissue, which is fundamentally made up of a viscous mucilage contained ... -
Ambulatory blood pressure monitoring and morning surge in blood pressure in adult black and white South Africans
(Wiley, 2020)We examined whether there were differences in the circadian variation in blood pressure and the morning surge in blood pressure between black and white Africans. Clinic and ambulatory blood pressure data obtained from the ... -
Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability
(Taylor & Francis, 2015)Azithromycin (AZM) is a poorly soluble macrolide antibacterial agent. Its low solubility is considered as the major contributing factor to its relatively low oral bioavailability. The aim of this study was to improve the ... -
Amorphous sulfadoxine: a physical stability and crystallization kinetics study
(Springer Nature, 2016)Poor aqueous solubility of drugs and the improvement thereof has always been a challenge for the pharmaceutical industry.With this, one of the focuses of the pharmaceutical research scientist involves investigating ... -
The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats
(Wolters Kluwer, 2009)Ampakines have shown beneficial effects on cognition in selected animal models of learning. However, their ability to modify long-term spatial memory tasks has not been studied yet. This would lend credence to their possible ... -
Amyloid fibril systems reduce, stabilize and deliver bioavailable nanosized iron
(Nature, 2017)Iron-deficiency anaemia (IDA) is a major global public health problem1. A sustainable and cost-effective strategy to reduce IDA is iron fortification of foods2, but the most bioavailable fortificants cause adverse organoleptic ... -
An evaluation of the community-based care and support services for older persons in a specific community
(Stellenbosch Univ, 2016)Community-based care and support services for older persons aim at enhancing their quality of life and keeping them in their communities for as long as possible. The aim of this study was to evaluate these services in a ... -
An only-child adolescent's lived experience of parental divorce
(SAPSAC, 2015)The aim of this qualitative case study was to explore and describe the experience of an only-child adolescent's lived experience of parental divorce. Gestalt field and phenomenological theory in conjunction with current ... -
An analysis of associations between electronic nicotine delivery system users
(AARC, 2020)BACKGROUND: Electronic nicotine-delivery systems have been increasing in prevalence among young adults. Although these devices are marketed to aid in quit smoking, young adults who do not smoke traditional cigarettes are ...