Browsing Faculty of Health Sciences by Title
Now showing items 818-837 of 2383
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Establishment and characterization of allograft and xenograft cancer rodent models
(Elsevier, 2019)To evaluate the efficacy of newly synthesized therapies prior to clinical trials, valid and true cancer models should be used [1]. For modelling cancer in vivo, transplantation of rodent (allograft) and human cancer ... -
Estimated carotid-femoral pulsewave velocity has similar predictive value as measured carotid-femoral pulse wave velocity
(Lippincott Williams & Wilkins, 2016)Background: Carotid–femoral pulse wave velocity (cfPWV) adds significantly to traditional cardiovascular risk prediction, but is not widely available. Therefore, it would be helpful if cfPWV could be replaced by an estimated ... -
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015
(Elsevier Inc, 2016)Background Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of ... -
Estimating an effect size in one-way multivariate analysis of variance (MANOVA)
(Taylor & Francis, 2009)When two or more univariate population means are compared, the proportion of variation in the dependent variable accounted for by population group membership is eta-squared. This effect size can be generalized by using ... -
Ethics and intergenerational programming: a critical reflection on historic environment education in South Africa
(Taylor & Francis, 2013)This article critically reflects on the ethical issues that emerged from an intergenerational project in post-Apartheid South Africa. An international organization from outside the South African borders utilized Time Travel ... -
Ethnic and gender differences regarding the insulin-blood pressure relationship
(Elsevier, 2009)Ageing is associated with increased insulin and C-peptide levels. Due to a lack of data, our first aim was to establish whether this also holds true for Africans from South Africa. Our second aim was to determine whether ... -
An ethnic comparison of arginine dimethylation and cardiometabolic factors in healthy black and white youth: the ASOS and African-PREDICT studies
(MDPI, 2020)Proteinic arginine dimethylation (PADiMe) is a major post-translational modification. Proteolysis of asymmetric and symmetric PADiMe products releases asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), ... -
Ethnic differences regarding arterial stiffness of 6‐8‐year-old black and white boys
(Wolters Kluwer, 2017)Objectives: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different ... -
Ethnic disparity in defensive coping endothelial responses: the SABPA study
(Elsevier, 2015)Objectives: Defensive coping (DefS) in Blacks has been associated with greater cardiovascular risk than in their White counterparts. We examined associations between endothelial function mental stress responses and markers ... -
Ethnic identification as contributor to the development of moral identity in child-headed households
(Taylor & Francis, 2013)This study explored whether ethnic membership was a core construct in the moral identity development of adolescents in Zulu child-headed households. A convenience sample of 60 participants (31 male and 29 female) were ... -
Ethnic-specific correlations of Visfatin with circulating markers of endothelial inflammation and function
(Wiley, 2009)Sub-Saharan Africa is afflicted by high hypertension prevalence that is expected to rise even further along with increasing obesity rates. The present study aimed to investigate the role of visfatin in obesity and to explore ... -
Ethnic-specific relationships between haemostatic and oxidative stress markers in black and white South Africans: the SABPA study
(Taylor & Francis, 2015)Haemostatic– and oxidative stress markers are associated with increased cardiovascular risk. In the black population, evidence exists that both an imbalance in the haemostatic system and oxidative stress link with the ... -
Ethnicity and arterial stiffness
(AHA, 2020)Early vascular aging reflects increased arterial stiffness of central blood vessels at young chronological ages and powerfully predicts cardiovascular events and mortality, independent of routine brachial blood pressure ... -
Ethnicity-specific changes in cardiac troponin t in response to acute mental stress and ethnicity-specific cutpoints for the R wave of the aVL lead: the SABPA study
(Oxford Univ Press, 2019)Acute mental stressor–induced cardiac stress responses might contribute to excessive myocardial strain and resultant cardiovascular episode risk. We assessed ethnicity-specific acute cardiac stress (by measuring cardiac ... -
Ethnicity-specific differences in L-arginine status in South African men
(Nature Publishing Group, 2012)The aetiology for an increasing incidence of hypertensive cardiovascular disease amongst Africans in southern Africa is unclear. Hypertension may be induced by inadequate release of L-arginine-derived nitric oxide impairing ... -
The eudaimonic and hedonic components of happiness: qualitative and quantitative findings
(Springer, 2011)This paper illustrates a new project developed by a cross-country team of researchers, with the aim of studying the hedonic and eudaimonic components of happiness through a mixed method approach combining both qualitative ... -
Eudragit® L100/N-trimethylchitosan chloride microspheres for oral insulin delivery
(MDPI, 2013)Effective oral delivery of protein and peptide drugs remains an active topic in scientific research. In this study, matrix type microspheres were prepared with Eudragit® L100 containing N-trimethylchitosan chloride to ... -
Euphorbias of South Africa: two new phorbol esters from Euphorbia bothae
(South African Bureau for Scientific Publications, 2010)Two known phorbol esters, 12-deoxyphorbol-13-isobutyrate-20-acetate (1) and 12-deoxyphorbol-13-(2-methylbutyrate)-20-acetate (2), and two new phorbol esters, 12-deoxyphorbol-13-isobutyrate-16-angelate-20-acetate (3) and ... -
European cardiovascular mortality over the last three decades: evaluation of time trends, forecasts for 2016
(Società Editrice Universo, 2017)Background. The circulatory diseases, in particular ischemic heart diseases and stroke, represent the main causes of death worldwide both in high income and in middle and low income countries. Our aim is to provide a ... -
Evaluating several biomarkers as predictors of aortic stiffness in young and older Africans, not consuming alcohol based on self-report
(Elsevier, 2018)Aims Black populations from sub-Saharan Africa have a high prevalence of cardiovascular disease, which places significant strain on public health systems. Aortic stiffness is a prominent risk factor for cardiovascular ...