Browsing Faculty of Health Sciences by Title
Now showing items 83-102 of 2386
-
Alcohol metabolism and health hazards associated with alcohol abuse in a South African context: a review
(Medpharm Publications, 2010)The World Health Organization recently stated that alcohol consumption is the fifth leading cause of death worldwide and that intakes are increasing, especially in developing countries. Alcohol-related effects are major ... -
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
(Elsevier, 2018)Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. ... -
Alcohol use and misuse among school-going adolescents in Thailand: results of a national survey in 2015
(MDPI, 2019)The aim of this study was to assess the prevalence of alcohol use and misuse, and to identify its associated factors among in-school adolescents in the 2015 Thailand Global School-based Student Health Survey (GSHS). The ... -
Aldosterone and renin in relation to surrogate measures of sympathetic activity: the SABPA study
(Clinics Cardive Publishing, 2019)Introduction: Hypertension, particularly in black populations, is often accompanied by augmented sympathetic nervous system activity and suppressed renin activity, indicative of possible blood pressure (BP) dysregulation. ... -
Alkaline phosphatase and arterial structure and function in hypertensive African men: the SABPA study
(Elsevier, 2013)Background: Vascular calcification is believed to be due to the conversion of vascular smooth muscle cells into osteoblast-like cells and is associated with mortality. Since hypertension and related mortality in Africans ... -
All headaches are not equal: a review of migraine as a state of brain dysfunction
(Taylor & Francis, 2018)Individuals suffering from migraine headache, or migraineurs as they are often referred to, and the clinicians treating them are well-informed of the excruciating and debilitating nature of such episodes. However, the ... -
Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression
(Springer Nature, 2013)Neuropeptide Y (NPY) has been implicated in depression, emotional processing and stress response. Part of this evidence originates from human single-nucleotide polymorphism (SNP) studies. In the present study, we report ... -
Aloe vera gel and whole leaf extract: functional and versatile excipients for drug delivery?
(Taylor & Francis, 2019)Aloe vera (L.) Burm.f. (Aloe barbadensis Miller) is a perennial xerophyte plant that has many medicinal applications. A. vera leaves contain water storage tissue, which is fundamentally made up of a viscous mucilage contained ... -
Ambulatory blood pressure monitoring and morning surge in blood pressure in adult black and white South Africans
(Wiley, 2020)We examined whether there were differences in the circadian variation in blood pressure and the morning surge in blood pressure between black and white Africans. Clinic and ambulatory blood pressure data obtained from the ... -
Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability
(Taylor & Francis, 2015)Azithromycin (AZM) is a poorly soluble macrolide antibacterial agent. Its low solubility is considered as the major contributing factor to its relatively low oral bioavailability. The aim of this study was to improve the ... -
Amorphous sulfadoxine: a physical stability and crystallization kinetics study
(Springer Nature, 2016)Poor aqueous solubility of drugs and the improvement thereof has always been a challenge for the pharmaceutical industry.With this, one of the focuses of the pharmaceutical research scientist involves investigating ... -
The ampakine, Org 26576, bolsters early spatial reference learning and retrieval in the Morris water maze: a subchronic, dose-ranging study in rats
(Wolters Kluwer, 2009)Ampakines have shown beneficial effects on cognition in selected animal models of learning. However, their ability to modify long-term spatial memory tasks has not been studied yet. This would lend credence to their possible ... -
Amyloid fibril systems reduce, stabilize and deliver bioavailable nanosized iron
(Nature, 2017)Iron-deficiency anaemia (IDA) is a major global public health problem1. A sustainable and cost-effective strategy to reduce IDA is iron fortification of foods2, but the most bioavailable fortificants cause adverse organoleptic ... -
An evaluation of the community-based care and support services for older persons in a specific community
(Stellenbosch Univ, 2016)Community-based care and support services for older persons aim at enhancing their quality of life and keeping them in their communities for as long as possible. The aim of this study was to evaluate these services in a ... -
An only-child adolescent's lived experience of parental divorce
(SAPSAC, 2015)The aim of this qualitative case study was to explore and describe the experience of an only-child adolescent's lived experience of parental divorce. Gestalt field and phenomenological theory in conjunction with current ... -
An analysis of associations between electronic nicotine delivery system users
(AARC, 2020)BACKGROUND: Electronic nicotine-delivery systems have been increasing in prevalence among young adults. Although these devices are marketed to aid in quit smoking, young adults who do not smoke traditional cigarettes are ... -
The ancient drug opium
(University of Stellenbosch, 2011)The use of papaver somniferum (from the Latin fero ferre = ‘tobear/bring’ and somnium = ‘sleep’) as a narcotic, goes backto the 13th century BC. The works of ancient authors such asDioscorides, Celsus, Galen, Theophrastus ... -
Animal models of major depressive disorder and the implications for drug discovery and development
(Taylor & Francis, 2019)Introduction: Depression is a highly debilitating psychiatric disorder that affects the global population and causes severe disabilities and suicide. Depression pathogenesis remains poorly understood, and the disorder is ... -
Antecedents of basic psychological need satisfaction of pharmacy students: the role of peers, family, lecturers and workload
(Elsevier, 2018)Background Self-determination theory (SDT) provides a model to improve pharmacy students' well-being or functioning in their study context. According to SDT, students need a context that satisfies their needs for autonomy, ...