Browsing Faculty of Health Sciences by Title
Now showing items 832-851 of 2386
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Ethnicity-specific changes in cardiac troponin t in response to acute mental stress and ethnicity-specific cutpoints for the R wave of the aVL lead: the SABPA study
(Oxford Univ Press, 2019)Acute mental stressor–induced cardiac stress responses might contribute to excessive myocardial strain and resultant cardiovascular episode risk. We assessed ethnicity-specific acute cardiac stress (by measuring cardiac ... -
Ethnicity-specific differences in L-arginine status in South African men
(Nature Publishing Group, 2012)The aetiology for an increasing incidence of hypertensive cardiovascular disease amongst Africans in southern Africa is unclear. Hypertension may be induced by inadequate release of L-arginine-derived nitric oxide impairing ... -
The eudaimonic and hedonic components of happiness: qualitative and quantitative findings
(Springer, 2011)This paper illustrates a new project developed by a cross-country team of researchers, with the aim of studying the hedonic and eudaimonic components of happiness through a mixed method approach combining both qualitative ... -
Eudragit® L100/N-trimethylchitosan chloride microspheres for oral insulin delivery
(MDPI, 2013)Effective oral delivery of protein and peptide drugs remains an active topic in scientific research. In this study, matrix type microspheres were prepared with Eudragit® L100 containing N-trimethylchitosan chloride to ... -
Euphorbias of South Africa: two new phorbol esters from Euphorbia bothae
(South African Bureau for Scientific Publications, 2010)Two known phorbol esters, 12-deoxyphorbol-13-isobutyrate-20-acetate (1) and 12-deoxyphorbol-13-(2-methylbutyrate)-20-acetate (2), and two new phorbol esters, 12-deoxyphorbol-13-isobutyrate-16-angelate-20-acetate (3) and ... -
European cardiovascular mortality over the last three decades: evaluation of time trends, forecasts for 2016
(Società Editrice Universo, 2017)Background. The circulatory diseases, in particular ischemic heart diseases and stroke, represent the main causes of death worldwide both in high income and in middle and low income countries. Our aim is to provide a ... -
Evaluating several biomarkers as predictors of aortic stiffness in young and older Africans, not consuming alcohol based on self-report
(Elsevier, 2018)Aims Black populations from sub-Saharan Africa have a high prevalence of cardiovascular disease, which places significant strain on public health systems. Aortic stiffness is a prominent risk factor for cardiovascular ... -
Evaluating the integrated management of childhood illness counselling skills of professional nurses in the North West Province of South Africa
(AOSIS, 2018)Background: The Integrated Management of Childhood Illness (IMCI) strategy provides guidelines for supporting and improving the health system to reduce under-5 children’s mortality rates. This strategy specifically assists ... -
Evaluation and optimization of synthetic routes from dihydroartemisinin to the alkylamino-artemisinins artemiside and artemisone: a test of N-glycosylation methodologies on a lipophilic peroxide
(Elsevier, 2018)10-Alkylamino-artemisinins including artemiside and artemisone display enhanced activities against malaria. Earlier, dihydroartemisinin (DHA) TMS ether was converted by trimethylsilyl bromide into the 10-β-bromide that ... -
The evaluation and quantification of respirable coal and silica dust concentrations: a task-based approach
(Taylor & Francis, 2014)Silicosis and coal worker's pneumoconiosis are serious occupational respiratory diseases associated with the coal mining industry and the inhalation of respirable dusts containing crystalline silica. The purpose of this ... -
The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase
(Elsevier, 2017)The monoamine oxidase (MAO) enzymes are of considerable pharmacological interest and inhibitors are used in the clinic for the treatment of major depressive disorder and Parkinson's disease. A limited number of studies ... -
The evaluation of 1-tetralone and 4-chromanone derivatives as inhibitors of monoamine oxidase
(Springer, 2020)Monoamine oxidase (MAO) is of much clinical relevance, and inhibitors of this enzyme are used in the treatment for neuropsychiatric and neurodegenerative disorders such as depression and Parkinson’s disease. The present ... -
Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A1 and A2A adenosine receptors
(Wiley, 2018)Antagonists of the adenosine receptors (A1 and A2A) are thought to be beneficial in neurological disorders, such as Alzheimer's and Parkinson's disease. The aim of this study was to explore 2-benzylidene-1-tetralone ... -
Evaluation of a flexible NOTA-RGD kit solution using Gallium-68 from different 68Ge/ 68Ga-generators: pharmacokinetics and biodistribution in nonhuman primates and demonstration of solitary pulmonary nodule imaging in humans
(Springer, 2016)Purpose: Radiopharmaceuticals containing the motive tripeptide arginyl-glycyl-asparatic acid (RGD) are known to target ανβ3 integrins during tumor angiogenesis. A more generic kit radiolabeling procedure accommodating ... -
Evaluation of a Health Setting-Based Stigma Intervention in Five African Countries
(Mary Ann Liebert, Inc., 2009)The study aim is to explore the results of an HIV stigma intervention in five African health care settings. A case study approach was used. The intervention consisted of bringing together a team of approximately 10 nurses ... -
Evaluation of a mass-media campaign to increase the awareness of the need to reduce discretionary salt use in the South African population
(MDPI, 2017)The South African strategic plan to reduce cardiovascular disease (CVD) includes reducing population salt intake to less than 5 g/day. A mass media campaign was undertaken to increase public awareness of the association ... -
The evaluation of an equine–assisted therapy programme with a group of boys in a youth care facility
(Taylor & Francis, 2015)The goal of this study was to evaluate the efficacy of an equine-assisted therapy programme aimed at improving the psychological well-being of boys in a custodial school of industry. Participants were 39 boys who live in ... -
Evaluation of community-based growth monitoring in rural districts of the Eastern Cape and KwaZulu-Natal provinces of South Africa
(MedPharm Publications, 2009)Background: The Health Systems Trust implemented a community-based growth-monitoring intervention project that fits into the Integrated Nutrition Programme focus areas and commissioned an evaluation of this project. ... -
Evaluation of emissions and exposures at workplaces using desktop 3-dimensional printers
(Elsevier, 2019)There is a paucity of data on additive manufacturing process emissions and personal exposures in real-world workplaces. Hence, we evaluated atmospheres in four workplaces utilizing desktop “3-dimensional” (3-d) printers ... -
The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs
(Elsevier, 2018)Introduction The sensitivity of a given test to detect a treatment-induced effect in a variable of interest is intrinsically related to the variability of that variable observed without treatment and the number of ...