Browsing Faculty of Health Sciences by Title
Now showing items 850-869 of 2386
-
Evaluation of emissions and exposures at workplaces using desktop 3-dimensional printers
(Elsevier, 2019)There is a paucity of data on additive manufacturing process emissions and personal exposures in real-world workplaces. Hence, we evaluated atmospheres in four workplaces utilizing desktop “3-dimensional” (3-d) printers ... -
The evaluation of endpoint variability and implications for study statistical power and sample size in conscious instrumented dogs
(Elsevier, 2018)Introduction The sensitivity of a given test to detect a treatment-induced effect in a variable of interest is intrinsically related to the variability of that variable observed without treatment and the number of ... -
Evaluation of isolated fractions of aloe vera gel materials on indinavir pharmacokinetics: in vitro and in vivo studies
(Bentham Science, 2016)Aloe vera is a plant with a long history of traditional medicinal use and is consumed in different products, sometimes in conjunction with prescribed medicines. A. vera gel has shown the ability to modulate drug absorption ... -
The evaluation of metal co-ordinating bis-thiosemicarbazones as potential anti-malarial agents
(Bentham Science, 2019)Background: The emergence of resistance to the artemisinins which are the current mainstays for antimalarial chemotheraphy has created an environment where the development of new drugs acting in a mechanistally discrete ... -
Evaluation of natural and synthetic 1,4-naphthoquinones as inhibitors of monoamine oxidase
(Wiley, 2016)Previous reports have documented that 1,4-naphtho- quinones act as inhibitors of the monoamine oxidase (MAO) enzymes. In particular, fractionation of the extracts of cured tobacco leafs has led to the charac- terization ... -
Evaluation of P-glycoprotein modulation by pharmaceutical excipients
(SAPJ, 2017)Modulation of P-glycoprotein (P-gp) may play a significant role in the systemic delivery of poorly bioavailable drugs e.g. anti-neoplastic drugs. Many compounds from different chemical classes, including pharmaceutical ... -
Evaluation of selected natural compounds as dual inhibitors of catechol-o-methyltransferase and monoamine oxidase
(Bentham Science, 2019)Background: The most effective symptomatic treatment of Parkinson’s disease remains the metabolic precursor of dopamine, L-dopa. To enhance the efficacy of L-dopa, it is often combined with inhibitors of the enzymes, ... -
An evaluation of synthetic indole derivatives as inhibitors of monoamine oxidase
(Elsevier, 2016)In a recent study we have shown that several indole-5,6-dicarbonitrile derivatives are potent inhibitors of human monoamine oxidase (MAO) A and B. To expand on these results and to further determine structure–activity ... -
The evaluation of the anti‐cancer drug elesclomol that forms a redox‐active copper chelate as a potential anti‐tubercular drug
(Wiley, 2019)The observations that the innate immune system employs copper toeliminate bacterial infection and that resistance to copper enhancesvirulence ofMycobacterium tuberculosis(Mtb) prompted us to exam-ine the effects the ... -
Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone mycotoxins
(Springer, 2017)Mycotoxins are toxic secondary metabolites produced by a range of fungi and are common contaminants of agricultural crops. These toxins are chemically diverse and structurally stable, enabling them to enter the food ... -
Evaluation of the in vitro antimicrobial activity of a Pheroid®- entrapped plant extract against human pathogens
(Elsevier, 2019)This plant extract (PE) has proven activity against fungi affecting crops in South Africa. However, there is currently insufficient data on the activity of the PE against human pathogens. The general aim of this study ... -
Evaluation of the mental health continuum-short form (MHC-SF) in Setswana-speaking South Africans
(Wiley, 2008)A continuous assessment and a categorical diagnosis of the presence of mental health, described as flourishing, and the absence of mental health, characterized as languishing, is applied to a random sample of 1050 ... -
Evaluation of the oral delivery of a peptide with Pheroid® technology
(Elsevier, 2019)Goserelin is a type of hormone therapy used in addition to standard adjuvant therapy. Currently, goserelin is only available as a slow releasing subcutaneous implant but this is an invasive and generally not well- tolerated ... -
Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine
(Elsevier, 2011)Stability data is used to determine the change the product has undergone over a certain time period at specific temperatures. In the present study, the physical stability characterized by size, pH and entrapment efficacy ... -
An evaluation of the purposes of research in social work
(Stellenbosch University, 2013)Different authors have varying opinions on what the purposes of research should be called. The terminology used in scientific writing should be understood to have a similar meaning by the various members of a particular ... -
Evaluation of the treatment guidelines, practices and outcomes of complicated severe acute malnutrition in children aged 0-59 months in sub-Saharan Africa: a study protocol for the SAMAC study
(Pan African Medical Journal, 2020)Introduction: in hospitals across Africa, the case fatality rates of severe acute malnutrition (SAM) have remained consistently high (over 20%), despite the existence of the WHO treatment guideline. This has been ... -
Evaluation of waist-to-height ratio to predict 5 year cardiometabolic risk in sub-Saharan African adults
(Open Access, 2014)Background and aims Simple, low-cost central obesity measures may help identify individuals with increased cardiometabolic disease risk, although it is unclear which measures perform best in African adults. We aimed to: ... -
Evaluative criteria applied by South African female fashion consumers when purchasing casual daywear
(Wiley, 2012)Criteria used by fashion consumers to assess the quality of apparel products during the decision-making process are a good indication of what considerations marketers and retailers should keep in mind for customer satisfaction. ... -
Evidence for time-dependent interactions between ritonavir and lopinavir/ritonavir plasma levels following P-glycoprotein inhibition in Sprague-Dawley rats
(Pharmaceutical Society of Japan, 2011)The interaction between verapamil, a P-glycoprotein (P-gp) inhibitor, with ritonavir and lopinavir/ritonavir (LPV/r) after acute and chronic treatment was investigated in rats. Rats were divided into 4 groups, viz. Group ... -
Evidence that fibrinogen y' regulates plasma clot structure and lysis and relationship to cardiovascular risk factors in black Africans
(The American Society of Hematology, 2013)No Abstract available