Browsing Faculty of Health Sciences by Author "Tanner, Lloyd"
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Accumulation of TB-active compounds in murine organs relevant to infection by mycobacterium tuberculosis
Tanner, Lloyd; Haynes, Richard K.; Wiesner, Lubbe (Frontiers Media, 2020)Tuberculosis (TB), the leading cause of death due to an infectious agent, requires prolonged and costly drug treatments. With the rise in incidence of MDR and XDR TB, newer more efficacious treatments which are better ... -
In vitro efficacies, ADME, and pharmacokinetic properties of phenoxazine derivatives active against Mycobacterium tuberculosis
Tanner, Lloyd; Haynes, Richard K.; Evans, Joanna C.; Seldon, Ronnett; Jordaan, Audrey (ASM, 2019)Mycobacterium tuberculosis, the causative agent of tuberculosis, remains a leading infectious killer globally, demanding the urgent development of faster-acting drugs with novel mechanisms of action. Riminophenazines such ...